The role and treatment potential of the complement pathway in chronic pain

M Vygonskaya, Y Wu, TJ Price, Z Chen, MT Smith… - The Journal of …, 2024 - Elsevier
The role of the complement system in pain syndromes has garnered attention on the back of
preclinical and clinical evidence supporting its potential as a target for new analgesic …

[HTML][HTML] Characterization of pain-related behaviors in a rat model of acute-to-chronic low back pain: single vs. multi-level disc injury

MF Barbe, FL Chen, RH Loomis, MY Harris… - Frontiers in Pain …, 2024 - ncbi.nlm.nih.gov
Methods Twenty-three Sprague-Dawley adult female rats were used: 8 received disc
puncture (DP) of one lumbar IVD (L5/6, DP-1); 8 received DP of two lumbar IVDs (L4/5 & …

Should cognitive behavioral therapy for insomnia be considered for preventing and managing chronic pain?

DM Klyne, SS Smith, M Hall - Sleep, 2024 - academic.oup.com
There is no question that chronic pain is one of the world's biggest health challenges and
current efforts to reduce the enormous burden of this condition are failing [1, 2]. Of all the …

Is sleep the new treatment for pain? Two issues need resolving before deciding

DM Klyne, M Hall - Sleep, 2024 - academic.oup.com
It is well known that chronic pain [1, 2] and poor sleep [3–5] are enormous and growing
health problems. Less recognized, however, is the relationship between the two. Poor sleep …