Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

Background Severe bleeding and coagulopathy are serious clinical conditions that are
associated with high mortality. Thromboelastography (TEG) and thromboelastometry …

Background Whether a restrictive threshold for hemoglobin level in red-cell transfusions, as
compared with a liberal threshold, reduces postoperative morbidity and health care costs …

Bleeding after cardiac surgery is a common and serious complication leading to transfusion
of multiple blood products and resulting in increased morbidity and mortality. Despite the …

Background This guideline addresses the management of patients who are receiving
anticoagulant or antiplatelet therapy and require an elective surgery or procedure. Methods …

Background Some observational studies have reported that transfusion of red-cell units that
have been stored for more than 2 to 3 weeks is associated with serious, even fatal, adverse …

Context Perioperative red blood cell transfusion is commonly used to address anemia, an
independent risk factor for morbidity and mortality after cardiac operations; however …

Background: Patients with substantive bleeding usually require transfusion and/or (re-)
operation. Red blood cell (RBC) transfusion is independently associated with a greater risk …

Among the influences of intraoperative anesthetic manage-ment that affect postoperative
mortality are low mean arterial pressure (MAP) and a deep hypnotic level (bispectral index …

The source of data was the American College of Surgeons National Surgical Quality
Improvement database of patients undergoing major noncardiac, nonemergency surgery at …