Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …

Ferroptosis is a newly discovered form of cell death that is featured in a wide range of
diseases. Exosome therapy is a promising therapeutic option that has attracted much …

Background Steatotic livers tolerate ischemia–reperfusion injury (IRI) poorly, increasing the
risk of organ dysfunction. Ferroptosis is considered the initiating factor of organ IRI. Heme …

Liver disease is prevalent worldwide. When it reaches the end stage, mortality rises to 50%
or more. Although liver transplantation has emerged as the most efficient treatment for end …

Hepatic ischemia-reperfusion injury (HIRI), a common two-phase intersocietal reaction in
liver surgery, typically leading to sustained liver dysfunction. During this process, liver …

The liver plays a significant role in regulating a wide range of metabolic, homeostatic, and
host-defense functions. However, the impact of liver injury on the host's ability to control …

Background Lung ischemia–reperfusion injury (LIRI) is a cause of poor prognosis in several
lung diseases and after lung transplantation. In LIRI, matrix metalloproteinases and …

Liver transplantation is the optimal treatment for patients with end-stage liver disease,
metabolic liver diseases, and hepatic malignancies that are not amenable to resection …

Rat orthotopic liver transplantation (ROLT) serves as an ideal animal model and has gained
popularity in addressing complications and perioperative treatments related to clinical liver …

Hepatic ischemia‒reperfusion injury (HIRI) is a common and inevitable complication of
hepatic trauma, liver resection, or liver transplantation. It contributes to postoperative organ …