Eukaryotic cilia and flagella are evolutionarily conserved organelles that protrude from the
cell surface. The unique location and properties of cilia allow them to function in vital …

The primary cilium has recently stepped into the spotlight, as a flood of data show that this
organelle has crucial roles in vertebrate development and human genetic diseases. Cilia …

The cilium is a complex organelle, the assembly of which requires the coordination of motor-
driven intraflagellar transport (IFT), membrane trafficking and selective import of cilium …

Cilia are ubiquitous eukaryotic organelles impotant for cellular motility, signaling, and
sensory reception. Cilium formation requires intraflagellar transport of structural and …

Both the basal body and the microtubule‐based axoneme it nucleates have evolutionarily
conserved subdomains crucial for cilium biogenesis, function and maintenance. Here, we …

Motile cilia are miniature, propeller-like extensions, emanating from many cell types across
the body. Their coordinated beating generates a directional fluid flow, which is essential for …

Membrane association with mother centriole (M-centriole) distal appendages is critical for
ciliogenesis initiation. How the Rab GTPase Rab11–Rab8 cascade functions in early ciliary …

Cilia are complex structures that have garnered interest because of their roles in vertebrate
development and their involvement in human genetic disorders. In contrast to multicellular …

Primary cilia are specialized microtubule‐based signaling organelles that convey
extracellular signals into a cellular response in most vertebrate cell types. The physiological …

Cilia and flagella have attracted tremendous attention in recent years as research
demonstrated crucial roles for these organelles in coordinating a number of physiologically …