The human ether-a-go-go related gene (hERG) encodes the pore-forming subunit of the
rapid component of the delayed rectifier K+ channel, Kv11. 1, which are expressed in the …

Potassium channels ubiquitously exist in nearly all kingdoms of life and perform diverse but
important functions. Since the first atomic structure of a prokaryotic potassium channel …

Ion channels represent the molecular entities that give rise to the cardiac action potential,
the fundamental cellular electrical event in the heart. The concerted function of these …

The light responses of rod and cone photoreceptors have been studied
electrophysiologically for decades, largely with ex vivo approaches that disrupt the …

The human voltage-sensitive K+ channel hERG plays a fundamental role in cardiac action
potential repolarization, effectively controlling the QT interval of the electrocardiogram …

This paper is the outcome of the fourth UC Davis Systems Approach to Understanding
Cardiac Excitation–Contraction Coupling and Arrhythmias Symposium, a biannual event …

Voltage-gated potassium channels are involved in many physiological processes such as
nerve impulse transmission, the heartbeat, and muscle contraction. However, for many of …

Abstract Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), poses an enormous challenge to the medical …

Mammalian ether‐à‐go‐go (EAG) channels are voltage‐gated K+ channels. They are
encoded by the KCNH gene family and divided into three subfamilies, eag (Kv10), erg (eag …

The fine tuning of biological electrical signaling is mediated by variations in the rates of
opening and closing of gates that control ion flux through different ion channels. Human …