Bioactive synthetic polymers

K Jung, N Corrigan, EHH Wong, C Boyer - Advanced Materials, 2022 - Wiley Online Library
Synthetic polymers are omnipresent in society as textiles and packaging materials, in
construction and medicine, among many other important applications. Alternatively, natural …

A review of the biomaterials technologies for infection-resistant surfaces

D Campoccia, L Montanaro, CR Arciola - Biomaterials, 2013 - Elsevier
Anti-infective biomaterials need to be tailored according to the specific clinical application.
All their properties have to be tuned to achieve the best anti-infective performance together …

A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset

W Chin, G Zhong, Q Pu, C Yang, W Lou… - Nature …, 2018 - nature.com
Polymyxins remain the last line treatment for multidrug-resistant (MDR) infections. As
polymyxins resistance emerges, there is an urgent need to develop effective antimicrobial …

Antimicrobial polymers: the potential replacement of existing antibiotics?

NF Kamaruzzaman, LP Tan, RH Hamdan… - International Journal of …, 2019 - mdpi.com
Antimicrobial resistance is now considered a major global challenge; compromising medical
advancements and our ability to treat infectious disease. Increased antimicrobial resistance …

Recent progress in polymer research to tackle infections and antimicrobial resistance

MM Konai, B Bhattacharjee, S Ghosh… - …, 2018 - ACS Publications
Global health is increasingly being threatened by the rapid emergence of drug-resistant
microbes. The ability of these microbes to form biofilms has further exacerbated the scenario …

Polymer brush coatings for combating marine biofouling

WJ Yang, KG Neoh, ET Kang, SLM Teo… - Progress in Polymer …, 2014 - Elsevier
A variety of functional polymer brushes and coatings have been developed for combating
marine biofouling and biocorrosion with much less environmental impact than traditional …

Biomimetic antimicrobial polymers: Recent advances in molecular design

C Ergene, K Yasuhara, EF Palermo - Polymer Chemistry, 2018 - pubs.rsc.org
The increasing prevalence of antibiotic-resistant bacterial infections, coupled with the
decline in the number of new antibiotic drug approvals, has created a therapeutic gap that …

Antimicrobial cationic polymers: From structural design to functional control

Y Yang, Z Cai, Z Huang, X Tang, X Zhang - Polymer Journal, 2018 - nature.com
Antimicrobial cationic polymers mainly contain two functional components: the cationic
groups and the hydrophobic groups. The antimicrobial activity is influenced by the type …

Poly (trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

K Fukushima - Biomaterials science, 2016 - pubs.rsc.org
Aliphatic polycarbonates have drawn attention as biodegradable polymers that can be
applied to a broad range of resorbable medical devices. In particular, poly (trimethylene …

Synthetic antimicrobial polymers in combination therapy: tackling antibiotic resistance

R Namivandi-Zangeneh, EHH Wong… - ACS Infectious …, 2021 - ACS Publications
Antibiotic resistance is a critical global healthcare issue that urgently needs new effective
solutions. While small molecule antibiotics have been safeguarding us for nearly a century …