The teeth are vertebrate-specific, highly specialized organs performing fundamental
functions of mastication and speech, the maintenance of which is crucial for orofacial …

The second most frequent craniomaxillofacial congenital deformity is hemifacial microsomia
(HFM). Patients often accompany short mandible, ear dysplasia, facial nerve, and soft tissue …

Single-cell chromatin accessibility sequencing (scATAC-seq) reconstructs developmental
trajectory by phenotypic similarity. However, inferring the exact developmental trajectory is …

Cranial sutures separate neighboring skull bones and are sites of bone growth. A key
question is how osteogenic activity is controlled to promote bone growth while preventing …

The genetic basis of human facial variation and craniofacial birth defects remains poorly
understood. Distant-acting transcriptional enhancers control the fine-tuned spatiotemporal …

The kinetics of redox couples based exclusively on peroxymonosulfate (PMS) are notably
slow and inefficient. In this study, urchin-like S v-MoS 2 were in situ deposited onto defect …

Research on the genetic mechanisms underlying human skeletal development and disease
have largely relied on studies in mice. However, recently the zebrafish has emerged as a …

Vertebrate calcitonin-producing cells (C-cells) are neuroendocrine cells that secrete the
small peptide hormone calcitonin in response to elevated blood calcium levels. Whereas …

The physiological and immune functions of fish gills are largely recognized, but their
following functional heterogeneity at the single cell scale has been rarely reported. Here, we …

Zebrafish (Danio rerio) are aquatic vertebrates with significant homology to their terrestrial
counterparts. While zebrafish have a centuries-long track record in developmental and …