Staphylococcus aureus is a formidable pathogen capable of causing infections in different
sites of the body in a variety of vertebrate animals, including humans and livestock. A major …

The human commensal bacterium Staphylococcus aureus can cause a wide range of
infections ranging from skin and soft tissue infections to invasive diseases like septicemia …

Thrombosis and infections are the main causes of implant failures (eg, extracorporeal
circuits and indwelling medical devices), which induce significant morbidity and mortality. In …

Fibrinogen, one of the most abundant plasma proteins playing a key role in hemostasis, is
an important modulator of wound healing and host defense against microbes. In the current …

Staphylococcus aureus biofilms, a leading cause of persistent infections, are highly resistant
to immune defenses and antimicrobial therapies. In the present study, we investigated the …

Background Rapid development of antibiotic resistance necessitates advancement of novel
therapeutic strategies to treat infection. Mesenchymal stromal cells (MSC) possess …

Fibrinogen is an essential part of the blood coagulation cascade and a major component of
the extracellular matrix in mammals. The interface between fibrinogen and bacterial …

Staphylococcus aureus is a commensal bacterium that has the ability to cause superficial
and deep-seated infections. Like several other invasive pathogens, S. aureus can capture …

Staphylococcus aureus produces numerous factors that facilitate survival in the human host.
S. aureus coagulase (Coa) and von Willebrand factor-binding protein (vWbp) are known to …

It is important to understand the microbial features of the cerebral thrombus and its clinical
relevance in stroke patients, of which data were scarce. We aimed to investigate the …