Oxidative stress is a phenomenon caused by an imbalance between production and
accumulation of oxygen reactive species (ROS) in cells and tissues and the ability of a …

Curcumin is a constituent (up to∼ 5%) of the traditional medicine known as turmeric. Interest
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …

Primary prevention through lifestyle interventions is a cost-effective alternative for preventing
a large burden of chronic and degenerative diseases, including cancer, which is one of the …

Triple-negative breast cancer (TNBC) is a subtype of breast cancer that is highly aggressive
and hypoxic compared with other subtypes. The role of hypoxia inducible factor 1α (HIF-1α) …

Covering: 2011 to 2014 It is widely accepted that drug discovery often requires a systems-
level polypharmacology approach to tackle problems such as lack of efficacy and emerging …

Reactive oxygen species (ROS) play a major role in carcinogenesis: pro-oxidant agents like
tobacco smoke, asbestos or N-nitrosamines, are known as mutagenic and carcinogenic, and …

Cancer is the second leading cause of death in humans. Despite rapid developments in
diagnostic methods and therapies, metastasis and resistance to administrated drugs are the …

The biggest drawback of a current diabetes therapy is the treatment of the consequences not
the cause of the disease. Regardless of the diabetes type, preservation and recovery of …

Butyrate is a short chain fatty acid derived from the microbial fermentation of dietary fibers in
the colon. In the last decade, multiple beneficial effects of butyrate at intestinal and …

Epigenetic inheritance and its underlying molecular mechanisms are among the most
intriguing areas of current biological and medical research. To date, studies have shown that …