The role of tumor microenvironment cells in colorectal cancer (CRC) cachexia

A Kasprzak - International journal of molecular sciences, 2021 - mdpi.com
Cancer cachexia (CC) is a multifactorial syndrome in patients with advanced cancer
characterized by weight loss via skeletal-muscle and adipose-tissue atrophy, catabolic …

Naringenin induces intrinsic and extrinsic apoptotic signaling pathways in cancer cells: A systematic review and meta-analysis of in vitro and in vivo data

F Faramarzi, M Alimohammadi, A Rahimi… - Nutrition Research, 2022 - Elsevier
Various reports show the beneficial effect of naringenin on the development of cancer. We
hypothesized that naringenin suppresses cancer cells by activating intrinsic and extrinsic …

Characterization of soluble dietary fiber from citrus peels (Citrus unshiu), and its antioxidant capacity and beneficial regulating effect on gut microbiota

Q Gu, X Gao, Q Zhou, Y Li, G Li, P Li - International Journal of Biological …, 2023 - Elsevier
This study aimed to evaluate the physicochemical, structural and functional properties of
soluble dietary fiber extracted from citrus peels (Citrus unshiu) by ultrasound-assisted …

Ultrasound-assisted development of stable grapefruit peel polyphenolic nano-emulsion: Optimization and application in improving oxidative stability of mustard oil

J Nishad, A Dutta, S Saha, SG Rudra, E Varghese… - Food chemistry, 2021 - Elsevier
Grapefruit (Citrus paradisi) peel (GP) is rich in flavonoids and phenolics which have several
proven pharmacological effects. However, their chemical instability towards oxygen, light …

Astaxanthin from Haematococcus pluvialis ameliorates the chemotherapeutic drug (doxorubicin) induced liver injury through the Keap1/Nrf2/HO-1 pathway in mice

H Ma, S Chen, H Xiong, M Wang, W Hang, X Zhu… - Food & function, 2020 - pubs.rsc.org
The aim of this study is to probe a new function of astaxanthin (AST) from Haematococcus
pluvialis on chemotherapeutic drug induced liver injury in mice. Doxorubicin-induced liver …

The role of natural products in the improvement of cancer-associated cachexia

Y Han, HI Kim, J Park - International Journal of Molecular Sciences, 2023 - mdpi.com
The enormous library of natural products and herbal medicine prescriptions presents
endless research avenues. However, the lack of research evidence and trials on cancer …

Targeted delivery of doxorubicin by Thermo/pH-responsive magnetic nanoparticles in a rat model of breast cancer

NMA Pourradi, H Babaei, H Hamishehkar… - Toxicology and Applied …, 2022 - Elsevier
The novel folate conjugated Thermo/pH-responsive magnetic nanoparticles (folate-poly-
MNPs) have been developed as a potential nanocarrier for improving site-specific drug …

Japanese herbal medicine ninjinyoeito mediates its orexigenic properties partially by activating orexin 1 receptors

K Miyano, K Ohshima, N Suzuki, S Furuya… - Frontiers in …, 2020 - frontiersin.org
Cancer cachexia is highly prevalent in patients with progressive cancer and is characterized
by decreased food consumption, and body weight. Japanese herbal medicine Ninjinyoeito …

[HTML][HTML] Ninjinyoeito ameliorates anorexia and changes in peptide YY and ghrelin levels of cisplatin-treated mice

A Hatae, T Watanabe, C Taniguchi, K Kubota… - Neuropeptides, 2024 - Elsevier
We explored the effect of Ninjinyoeito (NYT) on cisplatin-induced anorexia, which reduces
cancer patient survival. Both gastrointestinal motility and plasma concentrations of …

Anti‐inflammatory properties of an aldehydes‐enriched fraction of grapefruit essential oil

D Nikolic, L Bosco, M Moschetti… - Journal of Food …, 2023 - Wiley Online Library
Chronic inflammation is linked to the development of numerous diseases and is
accompanied by increased cytokine secretion. Macrophages provide a first line of defense …