New therapeutic strategies are needed to combat the tuberculosis pandemic and the spread
of multidrug-resistant (MDR) and extensively drug-resistant (XDR) forms of the disease …

Recent developments in the field of TB diagnostics, including the introduction of the Xpert
MTB/RIF assay in field testing, raise the hope for faster and more accurate identification of …

The global control of tuberculosis remains a challenge from the standpoint of diagnosis,
detection of drug resistance, and treatment. Because treatment can only be initiated when …

ABSTRACT Bedaquiline Drug Resistance Emergence Assessment in Multidrug-resistant
tuberculosis (MDR-TB)(DREAM) was a 5-year (2015 to 2019) phenotypic drug resistance …

Spontaneous mutants of Mycobacterium tuberculosis that were resistant to the anti‐
tuberculosis drugs ethionamide and isoniazid were isolated and found to map to mshA, a …

Objectives. We evaluated the safety of room occupants in the Tuberculosis Ultraviolet
Shelter Study (TUSS), a double-blind, placebo-controlled field trial of upper-room ultraviolet …

Tuberculosis is one of the major public health problems faced globally. Resistance of
Mycobacterium tuberculosis to antitubercular agents has called for an urgent need to …

Abstract A series of 1, 2, 3-trisubstituted indolizines (2a–2f, 3a–3d, and 4a–4c) were
screened for in vitro whole-cell anti-tubercular activity against the susceptible H37Rv and …

The alarming increase in multi-and extensively drug-resistant (MDR and XDR) strains of
Mycobacterium tuberculosis (MTB) has triggered the scientific community to search for …

We have screened 11 isoquinoline derivatives and α-methylene-γ-butyrolactones using the
3-(4, 5-dimethylthi-azol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) cytotoxicity assay in …