Tetrazole, a bioisostere of the carboxylic acid group, can replace the carboxyl group in drugs
to increase the lipophilicity, bioavailability and reduce side effects. Tetrazole derivatives …

Malaria is a life-threatening infectious disease caused by protozoal parasites belonging to
the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria …

Malaria can be caused by several Plasmodium species and the development of an effective
vaccine is challenging. Currently, the most effective tool to control the disease is the …

The demand for novel, fast‐acting, and effective antimalarial medications is increasing
exponentially. Multidrug resistant forms of malarial parasites, which are rapidly spreading …

In this work, we investigated in vitro different biological activities of alkaline lignins extracted
from the species Buchenavia viridiflora, a tree from the Amazon rainforest used as a wood …

Hypoglycemia is a clinical hallmark of severe malaria, the often-lethal outcome of
Plasmodium falciparum infection. Here, we report that malaria-associated hypoglycemia …

A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro
against intramacrophage amastigote forms of Leishmania donovani. All 15 tested …

Toxoplasmosis is an infectious disease with paramount impact worldwide, affecting many
vulnerable populations and representing a significant matter of concern. Current therapies …

Malaria, a mosquito‐borne parasitic infection caused by protozoan parasites belonging to
the genus Plasmodium, is a dangerous disease that contributes to millions of hospital visits …

The development of multidrug resistance in the malarial parasite has sabotaged majority of
the eradication efforts by restraining the inhibition profile of first line as well as second line …