CYP3A is an enzyme subfamily in the cytochrome P450 (CYP) superfamily and includes
isoforms CYP3A4, CYP3A5, CYP3A7, and CYP3A43. CYP3A enzymes are indiscriminate …

The interactions of two crucial proteins of COVID-19 have been investigated with potential
antiviral compounds from Moringa oliefera using quantum chemical, molecular docking and …

The cytochromes P450 comprise a family of enzymes that are responsible for around three-
quarters of all drug metabolism reactions that occur in human populations. Many isoforms of …

This work revises and complements existing findings on the distribution of drug‐
metabolizing enzymes in the first‐pass effect organs. We explored gene expression …

Variability in response to antiplatelet therapy can be explained in part by
pharmacogenomics, particularly of the CYP450 enzyme encoded by CYP2C19. Loss-of …

Aim The use of proton pump inhibitor (PPI) treatments are increasing among paediatric
patients worldwide. We aimed to review the effects of PPIs on the microbiome and its …

Cardiovascular ailments are the number one cause of mortalities throughout the globe with
17.9 million deaths per year. Platelet activation and aggregation play a crucial role in the …

Contamination is a potential problem in the study of ancient proteins, either from prior
handling of the sample, laboratory consumables, or cross-sample carryover from mass …

Diabetes mellitus is a metabolic disease that causes a hyperglycemic status which leads,
over time, to serious damage to the heart, blood vessels, eyes, kidneys and nerves. The …

Methylpyridinium 4-hydroxybenzoate (4MPH) has been investigated using calculations
involving quantum chemical computations. Conformer using least energy had been found to …