An overview on neurobiology and therapeutics of attention-deficit/hyperactivity disorder

BS Da Silva, EH Grevet, LCF Silva, JKN Ramos… - Discover Mental …, 2023 - Springer
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent psychiatric condition
characterized by developmentally inappropriate symptoms of inattention and/or …

Epigenetics and ADHD: reflections on current knowledge, research priorities and translational potential

CAM Cecil, JT Nigg - Molecular diagnosis & therapy, 2022 - Springer
Attention-deficit/hyperactivity disorder (ADHD) is a common and debilitating
neurodevelopmental disorder influenced by both genetic and environmental factors …

[HTML][HTML] Epigenome-wide DNA methylation in externalizing behaviours: a review and combined analysis

M Meijer, B Franke, C Sandi, M Klein - Neuroscience & Biobehavioral …, 2023 - Elsevier
DNA methylation (DNAm) is one of the most frequently studied epigenetic mechanisms
facilitating the interplay of genomic and environmental factors, which can contribute to …

DNA methylation is associated with prenatal exposure to sulfur dioxide and childhood attention-deficit hyperactivity disorder symptoms

YJ Choi, J Cho, YC Hong, D Lee, S Moon, SJ Park… - Scientific reports, 2023 - nature.com
Epigenetic influence plays a role in the association between exposure to air pollution and
attention deficit hyperactivity disorder (ADHD); however, research regarding sulfur dioxide …

Comprehensive analysis of omics data identifies relevant gene networks for Attention-Deficit/Hyperactivity Disorder (ADHD)

J Cabana-Domínguez, M Soler Artigas… - Translational …, 2022 - nature.com
Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental
disorder that results from the interaction of both genetic and environmental risk factors …

[HTML][HTML] Correlation of the methylomic signature of smoking during pregnancy with clinical traits in ADHD

B Chaumette, N Grizenko, W Fageera, MÈ Fortier… - Journal of Psychiatry and …, 2023 - jpn.ca
Background: Attention deficit/hyperactivity disorder (ADHD) is a highly prevalent childhood
disorder. Maternal smoking during pregnancy is a replicated environmental risk factor for …

Integrative multi‐omics analysis of genomic, epigenomic, and metabolomics data leads to new insights for Attention‐Deficit/Hyperactivity Disorder

N Hubers, FA Hagenbeek, R Pool… - American Journal of …, 2024 - Wiley Online Library
The evolving field of multi‐omics combines data and provides methods for simultaneous
analysis across several omics levels. Here, we integrated genomics (transmitted and non …

ADHD: the mammoth task of disentangling genetic, environmental, and developmental risk factors

S Kittel-Schneider - American Journal of Psychiatry, 2023 - Am Psychiatric Assoc
The first medical description of what is currently labeled attention deficit hyperactivity
disorder (ADHD) was published as early as the 18th century. The German physician …

Cortico-striatal differences in the epigenome in attention-deficit/hyperactivity disorder

GG Shastri, G Sudre, K Ahn, B Jung… - Translational …, 2024 - nature.com
While epigenetic modifications have been implicated in ADHD through studies of peripheral
tissue, to date there has been no examination of the epigenome of the brain in the disorder …

Polygenic risk score for attention‐deficit/hyperactivity disorder and brain functional networks segregation in a community‐based sample

JR Sato, CE Biazoli, APA Bueno, A Caye… - Genes, Brain and …, 2023 - Wiley Online Library
Neuroimaging studies suggest that brain development mechanisms might explain at least
some behavioural and cognitive attention‐deficit/hyperactivity disorder (ADHD) symptoms …