Abstract Purpose of Review To give an overview of the evolvement of transoral laser
microsurgery (TLM) in the treatment of early glottic carcinoma and highlight the contribution …

Introduction: The aim of the current systematic review is to update the pooled survival
outcome of patients with T2 glottic carcinoma treated with either laser surgery (CO2 transoral …

Laryngeal preservation for T2 tumours in this review is higher for patients treated primarily
with TLM (88.8 vs. 79.0%). It is important to differentiate between tumours with normal and …

The development of transoral laser microsurgery (TLM) was an important step in the history
of conservative laryngeal surgery. TLM reported comparable oncological outcomes and …

Positive margins are present in up to 50% of patients treated by TLM, even though a high
rate of false positivity, reaching 80%, has been described. Close and positive single …

Objective: For early glottic carcinoma, the 2 main treatment modalities are radiotherapy (RT)
and transoral CO2 laser microsurgery (TLM). The aim of this study was to investigate …

Purpose Treatment modalities for glottic cancer comprise surgery,(chemo-) radiation, and
combined treatment options. Glottic cancer involving the anterior commissure (AC) requires …

The classical adagium:'Failure to achieve negative margins indicates need for adjuvant
RT'does not translate automatically to patients with glottic cancer treated by TLM. Rather …

Early glottic cancer is typically defined as Tis, T1a, T1b, and T2 disease with no nodal
involvement (ie, stage 0, I, and II disease) and generally carries a favorable prognosis. 1 …

Purpose Laser transoral laryngeal microsurgery has become widely accepted treatment
method because of its organ and function preservation and shorter period of hospitalization …