One or several short cycles of ischemia/reperfusion before (preconditioning) or after
(postconditioning) a sustained coronary occlusion with subsequent reperfusion reduce the …

Medical gases are pharmaceutical molecules which offer solutions to a wide array of
medical needs. This can range from use in burn and stroke victims to hypoxia therapy in …

To investigate the effect of anti-cytokine-based therapy in the course of diabetic
cardiomyopathy, we performed a study using an anti-TNF-α monoclonal antibody treatment …

Background The study was designed to explore if sulfur dioxide (SO 2) preconditioning
increased antioxidative capacity in rat with myocardial ischemia reperfusion (I/R) injury …

Liver X receptor (LXR)-α and-β play a major role in lipid and glucose homeostasis. Their
expression and function in the heart is not well characterized. Our aim was to describe the …

Peroxiredoxin II, a cytosolic isoform of the antioxidant enzyme family, has been implicated in
cancer-associated cell death and apoptosis, but its functional role in the heart remains to be …

Aims Heart failure is associated with activation of fetal gene programs. Bone morphogenetic
proteins (BMPs) regulate embryonic development through interaction with BMP receptors …

Protein kinases are intimately integrated in different signal transduction pathways for the
regulation of cardiac function in both health and disease. Protein kinase A (PKA), Ca2+ …

AIMS: Gene therapy of a peripheral organ to protect the heart is clinically attractive. The
transcription factor hypoxia-inducible factor 1 alpha (HIF-1α) transactivates cardioprotective …

The purpose of this study was to determine if decreased heart function after hypoxia
followed by reoxygenation (H–R) is associated with increased degradation of cardiac …