Synaptic plasticity and mental health: methods, challenges and opportunities
Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that
allows neurons to communicate and change their connections as a function of past …
allows neurons to communicate and change their connections as a function of past …
TAPAS: an open-source software package for translational neuromodeling and computational psychiatry
Psychiatry faces fundamental challenges with regard to mechanistically guided differential
diagnosis, as well as prediction of clinical trajectories and treatment response of individual …
diagnosis, as well as prediction of clinical trajectories and treatment response of individual …
Association of thalamic dysconnectivity and conversion to psychosis in youth and young adults at elevated clinical risk
Importance Severe neuropsychiatric conditions, such as schizophrenia, affect distributed
neural computations. One candidate system profoundly altered in chronic schizophrenia …
neural computations. One candidate system profoundly altered in chronic schizophrenia …
Characterizing thalamo-cortical disturbances in schizophrenia and bipolar illness
Schizophrenia is a devastating neuropsychiatric syndrome associated with distributed brain
dysconnectivity that may involve large-scale thalamo-cortical systems. Incomplete …
dysconnectivity that may involve large-scale thalamo-cortical systems. Incomplete …
Prefrontal cortical dendritic spine pathology in schizophrenia and bipolar disorder
Importance Prior studies have demonstrated reduced dendritic spine density in the
dorsolateral prefrontal cortex (DLPFC) in schizophrenia. However, it remains unclear how …
dorsolateral prefrontal cortex (DLPFC) in schizophrenia. However, it remains unclear how …
[图书][B] Synaptic self: How our brains become who we are
J LeDoux - 2003 - books.google.com
In 1996 Joseph LeDoux's The Emotional Brain presented a revelatory examination of the
biological bases of our emotions and memories. Now, the world-renowned expert on the …
biological bases of our emotions and memories. Now, the world-renowned expert on the …
Meta-analysis of 41 functional neuroimaging studies of executive function in schizophrenia
MJ Minzenberg, AR Laird, S Thelen… - Archives of general …, 2009 - jamanetwork.com
Context Prefrontal cortical dysfunction is frequently reported in schizophrenia. It remains
unclear whether this represents the coincidence of several prefrontal region-and process …
unclear whether this represents the coincidence of several prefrontal region-and process …
The role of pro-inflammatory cytokines in the neuroinflammation and neurogenesis of schizophrenia
KS Na, HY Jung, YK Kim - Progress in Neuro-Psychopharmacology and …, 2014 - Elsevier
Schizophrenia is a serious mental illness with chronic symptoms and significant impairment
in psychosocial functioning. Although novel antipsychotics have been developed, the …
in psychosocial functioning. Although novel antipsychotics have been developed, the …
Disruption of cortical association networks in schizophrenia and psychotic bipolar disorder
Importance Psychotic disorders (including schizophrenia, schizoaffective disorder, and
psychotic bipolar disorder) are devastating illnesses characterized by breakdown in the …
psychotic bipolar disorder) are devastating illnesses characterized by breakdown in the …
Neurobiology of emotion perception II: Implications for major psychiatric disorders
To date, there has been little investigation of the neurobiological basis of emotion
processing abnormalities in psychiatric populations. We have previously discussed two …
processing abnormalities in psychiatric populations. We have previously discussed two …