Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval

D Hwang, JD Ramsey, AV Kabanov - Advanced drug delivery reviews, 2020 - Elsevier
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

Mucosal applications of poloxamer 407-based hydrogels: An overview

E Giuliano, D Paolino, M Fresta, D Cosco - Pharmaceutics, 2018 - mdpi.com
Poloxamer 407, also known by the trademark Pluronic® F127, is a water-soluble, non-ionic
triblock copolymer that is made up of a hydrophobic residue of polyoxypropylene (POP) …

Micelles structure development as a strategy to improve smart cancer therapy

NAN Hanafy, M El-Kemary, S Leporatti - Cancers, 2018 - mdpi.com
Micelles as colloidal suspension have attracted considerable attention due to their potential
use for both cancer diagnosis and therapy. These structures have proven their ability to …

Polymeric micelles as drug delivery vehicles

Z Ahmad, A Shah, M Siddiq, HB Kraatz - Rsc Advances, 2014 - pubs.rsc.org
Though much progress has been made in drug delivery systems, the design of a suitable
carrier for the delivery of hydrophobic drugs is still a major challenge for researchers. The …

Biomedical applications of biodegradable polymers

BD Ulery, LS Nair, CT Laurencin - Journal of polymer science …, 2011 - Wiley Online Library
Utilization of polymers as biomaterials has greatly impacted the advancement of modern
medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant …

Polymeric nanostructured materials for biomedical applications

Z Tang, C He, H Tian, J Ding, BS Hsiao, B Chu… - Progress in Polymer …, 2016 - Elsevier
Polymeric nanostructured materials (PNMs), which are polymeric materials in nanoscale or
polymer composites containing nanomaterials, have become increasingly useful for …

Nanogels as pharmaceutical carriers: finite networks of infinite capabilities

AV Kabanov, SV Vinogradov - … Chemie International Edition, 2009 - Wiley Online Library
Nanogels are swollen nanosized networks composed of hydrophilic or amphiphilic polymer
chains. They are developed as carriers for the transport of drugs, and can be designed to …

Poloxamer 188 as surfactant in biological formulations–An alternative for polysorbate 20/80?

L Bollenbach, J Buske, K Mäder, P Garidel - International Journal of …, 2022 - Elsevier
Surfactants are used to stabilize biologics. Particularly, polysorbates (Tween® 20 and
Tween® 80) dominate the group of surfactants in protein and especially antibody drug …

Micellar nanocarriers: pharmaceutical perspectives

VP Torchilin - Pharmaceutical research, 2007 - Springer
Micelles, self-assembling nanosized colloidal particles with a hydrophobic core and
hydrophilic shell are currently successfully used as pharmaceutical carriers for water …

Structure and design of polymeric surfactant-based drug delivery systems

VP Torchilin - Journal of controlled release, 2001 - Elsevier
The review concentrates on the use of polymeric micelles as pharmaceutical carriers.
Micellization of biologically active substances is a general phenomenon that increases the …