Precision medicine in the era of artificial intelligence: implications in chronic disease management

M Subramanian, A Wojtusciszyn, L Favre… - Journal of translational …, 2020 - Springer
Aberrant metabolism is the root cause of several serious health issues, creating a huge
burden to health and leading to diminished life expectancy. A dysregulated metabolism …

Early-life adversity and physical and emotional health across the lifespan: A neuroimmune network hypothesis

R Nusslock, GE Miller - Biological psychiatry, 2016 - Elsevier
Children who experience chronic stressors are vulnerable to emotional and physical health
problems across the lifespan. This phenomenon raises questions for scientists and …

Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms.

GE Miller, E Chen, KJ Parker - Psychological bulletin, 2011 - psycnet.apa.org
Among people exposed to major psychological stressors in early life, there are elevated
rates of morbidity and mortality from chronic diseases of aging. The most compelling data …

Central role of the brain in stress and adaptation: links to socioeconomic status, health, and disease

BS McEwen, PJ Gianaros - Annals of the New York Academy of …, 2010 - Wiley Online Library
The brain is the key organ of stress reactivity, coping, and recovery processes. Within the
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …

[HTML][HTML] Structural racism and its pathways to asthma and atopic dermatitis

A Martinez, R de la Rosa, M Mujahid… - Journal of Allergy and …, 2021 - Elsevier
Black, Latinx, and Indigenous people in the United States experience a disproportionate
burden of asthma and atopic dermatitis. The study of these disease disparities has focused …

Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention

JP Shonkoff, WT Boyce, BS McEwen - Jama, 2009 - jamanetwork.com
A scientific consensus is emerging that the origins of adult disease are often found among
developmental and biological disruptions occurring during the early years of life. These …

Psychological stress during childhood and adolescence and its association with inflammation across the lifespan: A critical review and meta-analysis.

JJ Chiang, PH Lam, E Chen, GE Miller - Psychological Bulletin, 2022 - psycnet.apa.org
Psychological stress during childhood and adolescence increases risk of health problems
across the lifecourse, and inflammation is implicated as an underlying mechanism. To …

Psychological science on pregnancy: stress processes, biopsychosocial models, and emerging research issues

C Dunkel Schetter - Annual review of psychology, 2011 - annualreviews.org
Psychological science on pregnancy is advancing rapidly. A major focus concerns stress
processes in pregnancy and effects on preterm birth and low birth weight. The current …

Childhood maltreatment and inflammatory markers: a systematic review

R Coelho, TW Viola, C Walss‐Bass… - Acta Psychiatrica …, 2014 - Wiley Online Library
Objective Childhood maltreatment (CM) has been associated with several diseases in adult
life, including diabetes, obesity and mental disorders. Inflammatory conditions have been …

Socioeconomic status and health: mediating and moderating factors

E Chen, GE Miller - Annual review of clinical psychology, 2013 - annualreviews.org
Health disparities (differences in health by socioeconomic groups) are a pressing issue in
our society. This article provides an overview of a multilevel approach that seeks to …