[HTML][HTML] Lymph node staging in colorectal cancer: old controversies and recent advances

A Resch, C Langner - World journal of gastroenterology: WJG, 2013 - ncbi.nlm.nih.gov
Outcome prediction based on tumor stage reflected by the American Joint Committee on
Cancer (AJCC)/Union for International Cancer Control (UICC) tumor node metastasis (TNM) …

The prognostic value of micrometastases and isolated tumour cells in histologically negative lymph nodes of patients with colorectal cancer: a systematic review and …

DAM Sloothaak, S Sahami… - European Journal of …, 2014 - Elsevier
Introduction Detection of occult tumour cells in lymph nodes of patients with stage I/II
colorectal cancer is associated with decreased survival. However, according to recent …

Hsa-miR-19a is associated with lymph metastasis and mediates the TNF-α induced epithelial-to-mesenchymal transition in colorectal cancer

L Huang, X Wang, C Wen, X Yang, M Song, J Chen… - Scientific reports, 2015 - nature.com
Lymph node metastasis is an important factor determining the outcome of colorectal cancer.
Although epithelial-to-mesenchymal transition (EMT), TNF-α and microRNA (miRNA) have …

[HTML][HTML] Long noncoding RNA GAPLINC promotes invasion in colorectal cancer by targeting SNAI2 through binding with PSF and NONO

P Yang, T Chen, Z Xu, H Zhu, J Wang, Z He - Oncotarget, 2016 - ncbi.nlm.nih.gov
This study aimed to investigate the role of long noncoding RNAs (lncRNAs) in the metastasis
of colorectal cancer (CRC). Metastasis is an important prognostic factor of CRC, and …

qRT‐PCR analysis of CEACAM5, KLK6, SLC35D3, MUC2 and POSTN in colon cancer lymph nodes—An improved method for assessment of tumor stage and …

G Lindmark, L Olsson, B Sitohy… - … Journal of Cancer, 2024 - Wiley Online Library
One fourth of colorectal cancer patients having curative surgery will relapse of which the
majority will die. Lymph node (LN) metastasis is the single most important prognostic factor …

Colorectal carcinoma grading by quantifying poorly differentiated cell clusters is more reproducible and provides more robust prognostic information than conventional …

V Barresi, L Reggiani Bonetti, G Branca, C Di Gregorio… - Virchows Archiv, 2012 - Springer
The most widely used system to define the histological grade of colorectal carcinoma (CRC)
is based on the degree of gland formation. This system suffers from significant interobserver …

Immune cells: plastic players along colorectal cancer progression

G Di Caro, F Marchesi, L Laghi… - Journal of cellular and …, 2013 - Wiley Online Library
Inflammatory cells are involved in tumour initiation and progression. In parallel, the adaptive
immune response plays a key role in fighting tumour growth and dissemination. The double …

Lymph node micrometastases and isolated tumor cells influence survival in stage I and II colon cancer

AE Faerden, OH Sjo, IRK Bukholm… - Diseases of the colon …, 2011 - journals.lww.com
PURPOSE: Lymph-node status is considered the most important prognostic factor in
colorectal cancer. The aim of the present prospective study was to evaluate the influence of …

Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer

SA Waldman, T Hyslop, S Schulz, A Barkun, K Nielsen… - Jama, 2009 - jamanetwork.com
Context The established relationship between lymph node metastasis and prognosis in
colorectal cancer suggests that recurrence in 25% of patients with lymph nodes free of tumor …

Immunohistochemical assessment of lymphovascular invasion in stage I colorectal carcinoma: prognostic relevance and correlation with nodal micrometastases

V Barresi, LR Bonetti, E Vitarelli… - The American journal …, 2012 - journals.lww.com
Several studies have suggested that the presence of occult nodal metastases
(micrometastases) is related to adverse clinical course in stage I colorectal carcinoma …