Advances in injectable hydrogel strategies for heart failure treatment

S He, Z Zhang, R Luo, Q Jiang, L Yang… - Advanced Healthcare …, 2023 - Wiley Online Library
Heart failure (HF) affects 60 million people worldwide and has developed into a global
public health problem surpassing cancer and urgently needs to be solved. According to the …

Dynamic responsiveness of self‐assembling peptide‐based nano‐drug systems

Y Wang, J Zhan, J Huang, X Wang… - Interdisciplinary …, 2023 - Wiley Online Library
Dynamic‐responsive self‐assembly is the process of ordered supramolecular structure
formation or reversible decomposition from building blocks. This process is driven by non …

Retinal Microenvironment‐Protected Rhein‐GFFYE Nanofibers Attenuate Retinal Ischemia‐Reperfusion Injury via Inhibiting Oxidative Stress and Regulating …

Z Zhang, S Peng, T Xu, J Liu, L Zhao, H Xu… - Advanced …, 2023 - Wiley Online Library
Retinal ischemia is involved in the occurrence and development of various eye diseases,
including glaucoma, diabetic retinopathy, and central retinal artery occlusion. To the best of …

Self-assembly hydrogels of therapeutic agents for local drug delivery

J Zheng, X Song, Z Yang, C Yin, W Luo, C Yin… - Journal of Controlled …, 2022 - Elsevier
Advanced drug delivery systems are of vital importance to enhance therapeutic efficacy.
Among various recently developed formulations, self-assembling hydrogels composed of …

Polyphenol-reinforced glycocalyx-like hydrogel coating induced myocardial regeneration and immunomodulation

H Wan, X Yang, Y Zhang, X Liu, Y Li, Y Qin, H Yan… - ACS …, 2024 - ACS Publications
Although minimally invasive interventional occluders can effectively seal heart defect tissue,
they still have some limitations, including poor endothelial healing, intense inflammatory …

Multifunctional cerium oxide nanozyme for synergistic dry eye disease therapy

H Zou, Y Hong, B Xu, M Wang, H Xie… - ACS Applied Materials …, 2024 - ACS Publications
Dry eye disease (DED) is a chronic multifactorial ocular surface disease mainly caused by
the instability of tear film, characterized by a series of ocular discomforts and even visual …

Fabrication of phosphatidylcholine-EGCG nanoparticles with sustained release in simulated gastrointestinal digestion and their transcellular permeability in a Caco-2 …

M Zhang, Y Su, J Li, C Chang, L Gu, Y Yang - Food Chemistry, 2024 - Elsevier
In this study, we prepared phosphatidylcholine (PC)-EGCG complex nanoparticles (PE NPs)
by solvent reflux method. The physicochemical properties, in vitro digestion, uptake in Caco …

Development of nanozymes for promising alleviation of COVID-19-associated arthritis

D Li, B Zhao, P Zhuang, X Mei - Biomaterials Science, 2023 - pubs.rsc.org
The COVID-19 pandemic caused by SARS-CoV-2 has been identified as a culprit in the
development of a variety of disorders, including arthritis. Although the emergence of arthritis …

Adaptive enzyme-responsive self-assembling multivalent apelin ligands for targeted myocardial infarction therapy

J Li, X Song, X Liao, Y Shi, H Chen, Q Xiao… - Journal of Controlled …, 2024 - Elsevier
Microvascular dysfunction following myocardial infarction exacerbates coronary flow
obstruction and impairs the preservation of ventricular function. The apelinergic system …

Low-intensity pulsed ultrasound of different intensities differently affects myocardial ischemia/reperfusion injury by modulating cardiac oxidative stress and …

Q Cao, L Liu, Y Hu, S Cao, T Tan, X Huang… - Frontiers in …, 2023 - frontiersin.org
Introduction The prevalence of ischemic heart disease has reached pandemic levels
worldwide. Early revascularization is currently the most effective therapy for ischemic heart …