The pandemic of COVID-19 is the biggest public health crisis in 21 st Century. Besides the
acute symptoms after infection, patients and society are also being challenged by the long …

The COVID-19 pandemic is the most severe pandemic caused by a respiratory virus since
the 1918 influenza pandemic. As is the case with other respiratory viruses, three modes of …

The Omicron lineage of SARS-CoV-2, which was first described in November 2021, spread
rapidly to become globally dominant and has split into a number of sublineages. BA. 1 …

Despite broad agreement on the negative consequences of vaccine inequity, the distribution
of COVID-19 vaccines is imbalanced. Access to vaccines in high-income countries (HICs) is …

It is unclear how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
leads to the strong but ineffective inflammatory response that characterizes severe …

The error rate displayed during template copying to produce viral RNA progeny is a
biologically relevant parameter of the replication complexes of viruses. It has consequences …

Summary In November 2021, Omicron BA. 1, containing a raft of new spike mutations,
emerged and quickly spread globally. Intense selection pressure to escape the antibody …

Vertebrate immune systems suppress viral infection using both innate restriction factors and
adaptive immunity. Viruses mutate to escape these defenses, driving hosts to counterevolve …

The nucleocapsid (N-) protein of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has a key role in viral assembly and scaffolding of the viral RNA. It promotes liquid …

The COVID-19 pandemic has posed enormous challenges for existing diagnostic tools to
detect and monitor pathogens. Therefore, there is a need to develop point-of-care (POC) …