Reactive oxygen species (ROS) react preferentially with certain atoms to modulate functions
ranging from cell homeostasis to cell death. Molecular actions include both inhibition and …

Stem cell ageing underlies the ageing of tissues, especially those with a high cellular
turnover. There is growing evidence that the ageing of the immune system is initiated at the …

Despite the importance of cell fusion for mammalian development and physiology, the
factors critical for this process remain to be fully defined, which has severely limited our …

Although the function of the autonomic nervous system (ANS) in mediating the flight-or-fight
response was recognized decades ago, the crucial role of peripheral innervation in …

Upon aging, hematopoietic stem cells (HSC s) undergo changes in function and structure,
including skewing to myeloid lineages, lower reconstitution potential and loss of protein …

In recent years, technical developments in mouse genetics and imaging equipment have
substantially advanced our understanding of hematopoietic stem cells (HSCs) and their …

Injectable thermo-sensitive hydrogels composed of small intestinal submucosa (SIS) with
exosomes derived from bone marrow mesenchymal stem cells (BMSCs) are desired for …

The bone marrow (BM) niche comprises multiple cell types that regulate hematopoietic
stem/progenitor cell (HSPC) migration out of the niche and into the circulation. Here, we …

The fate of hematopoietic stem and progenitor cells (HSPC) is tightly regulated by their bone
marrow (BM) microenvironment (ME). BM transplantation (BMT) frequently requires …

Connexin43 (Cx43) is the most abundant gap junction protein expressed in bone cells and
plays a central role in cell-to-cell communication in the skeleton. Findings of the last decade …