Biodegradable hydrophobic injectable polymers for drug delivery and regenerative medicine

Y Arun, R Ghosh, AJ Domb - Advanced Functional Materials, 2021 - Wiley Online Library
Biodegradable, hydrophobic, and injectable liquid polymers are capable of achieving the
minimally invasive, sustained, and local release of drugs. These hydrophobic injectable …

Cells-based drug delivery for cancer applications

Y Du, S Wang, M Zhang, B Chen, Y Shen - Nanoscale research letters, 2021 - Springer
The application of cells as carriers to encapsulate chemotherapy drugs is of great
significance in antitumor therapy. The advantages of reducing systemic toxicity, enhancing …

In vivo degradation mechanisms of aliphatic polycarbonates and functionalized aliphatic polycarbonates

B Amsden - Macromolecular Bioscience, 2021 - Wiley Online Library
Aliphatic polycarbonates (APCs) have been studied for decades but have not been as
utilized as aliphatic polyesters in biomaterial applications such as drug delivery and tissue …

Degradation of poly (vinyl sulfone carbonate) in aqueous media

H Riahinezhad, N Kerr-Dini, BG Amsden - Polymer Degradation and …, 2023 - Elsevier
A cyclic vinyl sulfone carbonate monomer has previously been developed and used to
prepare degradable polymers through ring-opening copolymerization with cyclic ester …

Biodegradable implants based on photo-cross-linked aliphatic polycarbonates for long-acting contraception

Z Hou, W Xu, S Chen, J Guo, P Li, J Hu, L Yang… - Journal of Materials …, 2023 - Elsevier
In this study, a new class of biodegradable contraceptive implants was prepared via the UV
irradiation molding method, among which, progestin levonorgestrel (LNG) was used as a …

End Group Dye‐Labeled Polycarbonate Block Copolymers for Micellar (Immuno‐) Drug Delivery

C Czysch, C Medina‐Montano, NJK Dal… - Macromolecular …, 2022 - Wiley Online Library
Defined conjugation of functional molecules to block copolymer end groups is a powerful
strategy to enhance the scope of micellar carriers for drug delivery. In this study, an …

In vitro enzymatic degradation of the PTMC/cross-linked PEGDA blends

W Li, M Lin, C Wang, Y Lu, Y Sui, X Ni, J Guo… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: Poly (1, 3-trimethylene carbonate)(PTMC) is a flexible amorphous polymer with
good degradability and biocompatibility. The degradation of PTMC is critical for its …

Long-term in vivo degradation behavior of poly (trimethylene carbonate-co-2, 2′-dimethyltrimethylene carbonate)

Z Hou, S Chen, W Hu, J Guo, P Li, J Hu… - European Polymer …, 2022 - Elsevier
Abstract Poly (trimethylene carbonate-co-2, 2′-dimethyltrimethylene carbonate) P (TMC-co-
DTC) copolymers with different molecular weights or molar ratios were prepared by bulk ring …

Enhanced anti-tumor efficacy and tumor accumulation of Tamoxifen through cRGD functionalized cholesterol based lipopolymeric nanoparticles for targeted breast …

S Mazumdar, S Narisepalli, AK Singh… - Journal of Drug Delivery …, 2023 - Elsevier
Targeting ligand mediated drug delivery systems hold promise for enhancing the anti-tumor
efficacy and suppressing the off-target effects of chemotherapeutic molecules. The current …

Nontoxic N-Heterocyclic Olefin Catalyst Systems for Well-Defined Polymerization of Biocompatible Aliphatic Polycarbonates

C Czysch, T Dinh, Y Fröder, L Bixenmann… - ACS polymers …, 2022 - ACS Publications
Herein, N-heterocyclic olefins (NHOs) are utilized as catalysts for the ring-opening
polymerization (ROP) of functional aliphatic carbonates. This emerging class of catalysts …