Motivated by the conceptual framework of multi-scale biomechanics, this narrative review
highlights recent major advances with a focus on gait and joint kinematics, then tissue-level …

Abstract Purpose of Review Osteocytes are the conductors of bone adaptation and
remodelling. Buried inside the calcified matrix, they sense mechanical cues and signal …

Tumor properties such as growth and metastasis are dramatically dependent on the tumor
microenvironment (TME). However, the diversity of the TME including the stiffness and the …

The tumor microenvironment (TME) is distinctly heterogeneous and is involved in tumor
growth, metastasis, and drug resistance. Mimicking this diverse microenvironment is …

摘要背景: 关于骨关节炎的病因目前尚不完全明确, 目前有大量关于软骨退变, 软骨下骨退化,
关节力学改变, 神经传导异常等多种发病机制的研究, 近年来对骨关节炎的各种致病因素有大量 …

Cell migration is essential for regulating many biological processes in physiological or
pathological conditions, including embryonic development and cancer invasion. In vitro and …

It is well-known that cell adhesion is important in many biological processes such as cell
migration and proliferation. A better understanding of the cell adhesion process will shed …

Methotrexate is a commonly used anti-cancer chemotherapy drug. Cellular mechanical
properties are fundamental parameters that reflect the physiological state of a cell. However …

Heterogeneous intercellular coupling plays a significant role in mechanical and electrical
signal transmission in the heart. Although many studies have investigated the electrical …

Cellular responses to mechanical stimuli are influenced by the mechanical properties of
cells and the surrounding tissue matrix. Cells exhibit viscoelastic behavior in response to an …