Comorbidities in spondyloarthritis (SpA) add to the burden of disease by contributing to
disease activity, functional and work disability, and mortality. Thus, awareness of …

Rheumatoid arthritis (RA) is a chronic progressive autoimmune disease. Despite the wide
use of conventional synthetic, targeted and biologic disease modifying anti-rheumatic drugs …

Objective The aim of this study was to update the Japan College of Rheumatology (JCR)
clinical practice guidelines (CPG) for the management of rheumatoid arthritis (RA; JCR CPG …

Network medicine has improved the mechanistic understanding of disease, offering
quantitative insights into disease mechanisms, comorbidities, and novel diagnostic tools and …

Psoriasis is a chronic, systemic, inflammatory disease that is often associated with serious
comorbid conditions such as cardiovascular disease, obesity, and diabetes. Many patients …

The link between cancer and rheumatoid arthritis (RA) is complex. With advances in the
knowledge of the pathophysiology, long-term outcomes, and development of new agents for …

Objectives To explore the risk of new and recurrent cancer in adult RA patients with prior
malignancy and subsequently exposed to biologic therapies. Methods Separate searches …

Objectives To systematically review the impact of tapering targeted therapies (bDMARDs or
JAKis) on the risk of serious infections and severe adverse events (SAEs) in patients with …

Healthcare systems worldwide are struggling to find ways to fund the cost of innovative
treatments such as gene therapies, regenerative medicine, and monoclonal antibodies …

Comorbidities in spondyloarthritis (SpA) including psoriatic arthritis have to be differentiated
to the concept of clinical features of SpA (eg, uveitis, psoriasis, and inflammatory bowel …