Biomaterials have had an increasingly important role in recent decades, in biomedical
device design and the development of tissue engineering solutions for cell delivery, drug …

Bone tissue has a remarkable ability to regenerate and heal itself. However, large bone
defects and complex fractures still present a significant challenge to the medical community …

Novel tissue regeneration strategies are constantly being developed worldwide. Research
on bone regeneration is noteworthy, as many promising new approaches have been …

Joint replacement is a major orthopaedic procedure used to treat joint osteoarthritis. Aseptic
loosening and infection are the two most significant causes of prosthetic implant failure. The …

Critical‐sized defects in bone, whether induced by primary tumor resection, trauma, or
selective surgery have in many cases presented insurmountable challenges to the current …

In modern technology, there is a constant need to solve very complex problems and to fine-
tune existing solutions. This is definitely the case in modern medicine with emerging fields …

Objective: The aim of the present review was to evaluate the bone integration efficacy of
recently developed and marketed oral implants as well as experimental surface alterations …

Titanium (Ti) plays a predominant role as the material of choice in orthopaedic and dental
implants. Despite the majority of Ti implants having long-term success, premature failure due …

Engineering biomaterials that mimic the extracellular matrix (ECM) of bone is of significant
importance since most of the outstanding properties of the bone are due to matrix …

Generally, medical implants, regardless of their construction materials, will become coated
in a layer of nonspecific proteins mere seconds after implantation. This adsorbed layer …