Mechanisms of action of kefir in chronic cardiovascular and metabolic diseases

FS Pimenta, M Luaces-Regueira, AMM Ton… - Cellular Physiology and …, 2018 - karger.com
The gut microbiota maintains a complex mutual interaction with different organs of the host.
Whereas in normal conditions this natural community of trillions of microorganisms greatly …

The emerging scenario of the gut–brain axis: the therapeutic actions of the new actor kefir against neurodegenerative diseases

TMC Pereira, LZ Côco, AMM Ton, SS Meyrelles… - Antioxidants, 2021 - mdpi.com
The fact that millions of people worldwide suffer from Alzheimer's disease (AD) or
Parkinson's disease (PD), the two most prevalent neurodegenerative diseases (NDs), has …

Oxidative stress and dementia in Alzheimer's patients: effects of synbiotic supplementation

AMM Ton, BP Campagnaro, GA Alves… - Oxidative medicine …, 2020 - Wiley Online Library
Background. Alzheimer's disease (AD) is the most common cause of dementia in elderly
patients. Recently, several studies have shown that inflammation and oxidative stress …

Renoprotective, anti-oxidative and anti-apoptotic effects of oral low-dose quercetin in the C57BL/6J model of diabetic nephropathy

IBS Gomes, ML Porto, MCLFS Santos… - Lipids in Health and …, 2014 - Springer
Background Diabetic nephropathy (DN) is one of the major causes of end-stage renal
disease in diabetic patients. Increasing evidence from studies in the rodents has suggested …

Chronic Cadmium Exposure Accelerates the Development of Atherosclerosis and Induces Vascular Dysfunction in the Aorta of ApoE−/− Mice

TF Oliveira, PR Batista, MA Leal… - Biological trace element …, 2019 - Springer
Cadmium exposure is related to cardiovascular diseases, including hypertension,
atherosclerosis, increased oxidative stress, endothelial dysfunction, and specific …

Gastroprotective effect of oral kefir on indomethacin-induced acute gastric lesions in mice: Impact on oxidative stress

KRM Barboza, LZ Coco, GM Alves, B Peters… - Life Sciences, 2018 - Elsevier
Aims This study investigated the gastroprotective effects and the systemic oxidative status of
oral kefir pretreatment in albino mice submitted to acute gastric ulcer induced by …

Unravelling the gastroprotective potential of Kefir: exploring antioxidant effects in preventing gastric ulcers

LZ Côco, R Aires, GR Carvalho, ES Belisário, MKK Yap… - Cells, 2023 - mdpi.com
The present study was conducted to evaluate the protective effect of milk kefir against NSAID-
induced gastric ulcers. Male Swiss mice were divided into three groups: control (Vehicle; …

Bisphenol A contamination in infant rats: Molecular, structural, and physiological cardiovascular changes and the protective role of kefir

AGF Friques, FDN Santos, DB Angeli, FAC Silva… - The Journal of …, 2020 - Elsevier
The effects of bisphenol A (BPA) contamination on the cardiovascular function still are not
clear. Here, we evaluated the vascular effects of BPA and the protective actions of kefir in …

Sildenafil ameliorates oxidative stress and DNA damage in the stenotic kidneys in mice with renovascular hypertension

AT Dias, BP Rodrigues, ML Porto, AL Gava… - Journal of translational …, 2014 - Springer
Background Oxidative stress and DNA damage have been implicated in the pathogenesis of
renovascular hypertension induced by renal artery stenosis in the two-kidney, one-clip …

[HTML][HTML] Tributyltin chloride induces renal dysfunction by inflammation and oxidative stress in female rats

JVS Coutinho, LC Freitas-Lima, FFCT Freitas… - Toxicology Letters, 2016 - Elsevier
Tributyltin chloride (TBT) is an organometallic pollutant that is used as a biocide in
antifouling paints. TBT induces several toxic and endocrine-disrupting effects. However …