The micronucleus assay in human buccal cells as a tool for biomonitoring DNA damage: the HUMN project perspective on current status and knowledge gaps

N Holland, C Bolognesi, M Kirsch-Volders… - … Research/Reviews in …, 2008 - Elsevier
The micronucleus (MN) assay in exfoliated buccal cells is a useful and minimally invasive
method for monitoring genetic damage in humans. This overview has concluded that …

The HUman MicroNucleus Project—an international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans

M Fenech, N Holland, WP Chang, E Zeiger… - Mutation Research …, 1999 - Elsevier
The International Collaborative Project on Micronucleus Frequency in Human Populations
(HUMN) was organized to collect data on micronucleus (MN) frequencies in different human …

Buccal micronucleus cytome assay

P Thomas, N Holland, C Bolognesi, M Kirsch-Volders… - Nature protocols, 2009 - nature.com
Abstract The Buccal Micronucleus Cytome (BMCyt) assay is a minimally invasive method for
studying DNA damage, chromosomal instability, cell death and the regenerative potential of …

Biomonitoring of four European populations occupationally exposed to pesticides: use of micronuclei as biomarkers

S Pastor, A Creus, T Parrón… - …, 2003 - academic.oup.com
This paper presents the results obtained within the framework of an EU research project
aimed at investigating the relationship between occupational exposure to pesticides and the …

Occupational exposure to pesticides and cytogenetic damage: results of a Hungarian population study using the micronucleus assay in lymphocytes and buccal cells

S Pastor, A Creus, N Xamena, C Siffel… - Environmental and …, 2002 - Wiley Online Library
The frequency of micronuclei (MN) in peripheral blood lymphocytes and in buccal epithelial
cells was used as a biomarker of genotoxic effects resulting from occupational exposure to …

Use of the micronucleus assay with exfoliated epithelial cells as a biomarker for monitoring individuals at elevated risk of genetic damage and in chemoprevention …

BJ Majer, B Laky, S Knasmüller, F Kassie - Mutation Research/Reviews in …, 2001 - Elsevier
This review summarises the current database on the micronucleus (MN) assay with
exfoliated cells (MEC assay) and evaluates the predictive value of this model for the …

Micronuclei assay of exfoliated oral buccal cells: means to assess the nuclear abnormalities in different diseases

B Kashyap, PS Reddy - Journal of cancer research and …, 2012 - journals.lww.com
The micronuclei assay (MA) in exfoliated buccal cells is an innovative genotoxicity
technique, which holds promise for the study of epithelial carcinogens. Micronuclei are …

Biological and environmental monitoring of hospital personnel exposed to antineoplastic agents: a review of analytical methods

R Turci, C Sottani, G Spagnoli, C Minoia - Journal of Chromatography B, 2003 - Elsevier
In order to assess occupational exposure of hospital personnel involved in the preparation
and administration of antineoplastic drugs, biological and environmental monitoring are …

Genetic monitoring of malathion‐exposed agricultural workers

GC Windham, N Titenko‐Holland… - American journal of …, 1998 - Wiley Online Library
The aerial application of malathion over large urban populations in Southern California
during the early 1990s raised concerns about adverse health effects, including the potential …

Cinnamic acid induces apoptotic cell death and cytoskeleton disruption in human melanoma cells

ELO Niero, GM Machado-Santelli - Journal of experimental & clinical …, 2013 - Springer
Anticancer activities of cinnamic acid derivatives include induction of apoptosis by
irreversible DNA damage leading to cell death. The present work aimed to compare the …