Alcohol tolerance refers to a lower effect of alcohol with repeated exposure. Although
alcohol tolerance has been historically included in diagnostic manuals as one of the key …

Drosophila melanogaster has become a significant model organism for alcohol research. In
flies, a rich variety of behaviors can be leveraged for identifying genes affecting alcohol …

Alcohol use disorder (AUD) exacts an immense toll on individuals, families, and society.
Genetic factors determine up to 60% of an individual's risk of developing problematic alcohol …

Alcohol abuse is a significant public health problem. While considerable research has
shown that alcohol use affects sleep, little is known about the role of sleep deprivation in …

Our understanding of the networks of genes and protein functions involved in Alcohol Use
Disorder (AUD) remains incomplete, as do the mechanisms by which these networks lead to …

Alcohol tolerance is a neuroadaptive response that leads to a reduction in the effects of
alcohol caused by previous exposure. Tolerance plays a critical role in the development of …

The ability to adapt to environmental changes is an essential feature of biological systems,
achieved in animals by a coordinated crosstalk between neuronal and hormonal programs …

Homeostatic neural adaptations to alcohol underlie the production of alcohol tolerance and
the associated symptoms of withdrawal. These adaptations have been shown to persist for …

Alcohol addiction is a serious condition perpetuated by enduring physiological and
behavioral adaptations. An important component of these adaptations is the long-term …

Simple Summary The role of two biomarkers, heat shock protein 70 (HSP70) and big
potassium ion channel protein (BKP), in the development of functional ethanol tolerance is …