Lipid-based nanovesicular drug delivery systems

T Limongi, F Susa, M Marini, M Allione, B Torre… - Nanomaterials, 2021 - mdpi.com
In designing a new drug, considering the preferred route of administration, various
requirements must be fulfilled. Active molecules pharmacokinetics should be reliable with a …

Recent advances and future prospective of topical and transdermal delivery systems

P Tapfumaneyi, M Imran, Y Mohammed… - Frontiers in Drug …, 2022 - frontiersin.org
Recent advances in topical and transdermal drug delivery systems have enabled targeted
delivery of therapeutics to the site of action by enhancing drug permeation across the …

[HTML][HTML] Novel lipid nanovesicle-loaded dissolving microarray patches for fenretinide in breast cancer chemoprevention

AC Apolinário, YA Naser, F Volpe-Zanutto… - Journal of Controlled …, 2024 - Elsevier
The retinoid fenretinide (FENR) is a promising compound for preventing breast cancer
recurrence but faces challenges due to poor solubility and low bioavailability. This study …

A comprehensive review of the biomaterial-based multifunctional nanocarriers for therapeutic applications in breast cancer

A Shettiwar, U Gupta, P Paul, R Nair, M Aalhate… - Journal of Drug Delivery …, 2023 - Elsevier
Breast cancer is among the most dreadful malignancies in women causing the highest
mortality across the globe. The prevalent therapies have not been able to be efficacious to …

Quality-by-design-based engineered liposomal nanomedicines to treat cancer: an in-depth analysis

D Kapoor, S Sharma, K Verma, A Bisht, M Sharma… - …, 2022 - Taylor & Francis
Engineered nano-sized liposomes have attained the highest success rate in
commercialization among the reported nanomedicines. However, developing industrially …

Rethinking breast cancer chemoprevention: technological advantages and enhanced performance of a nanoethosomal-based hydrogel for topical administration of …

AC Apolinário, GC Salata, MM de Souza, M Chorilli… - AAPS …, 2022 - Springer
Herein, we developed an ethosomal hydrogel based on three types of ethosomes: simple,
mixed (surfactant-based micelles and lipid vesicles) or binary (comprising two type of …

Exploring contemporary breakthroughs in utilizing vesicular nanocarriers for breast cancer therapy

NU Kumari, E Pardhi, PS Chary, NK Mehra - Therapeutic Delivery, 2024 - Taylor & Francis
Breast cancer (BC) is a heterogeneous disease with various morphological features,
clinicopathological conditions and responses to different therapeutic options, which is …

Aquasomes: a novel platform for drug delivery

M İlhan, HE Gültekin, S Rençber, Z Şenyiğit… - … of Nanovesicular Drug …, 2022 - Elsevier
In recent years, drug research has focused on nanocarrier systems. Self-assembled
nanodrug delivery systems such as liposome, niosome, polymersome, and transfersome …

[HTML][HTML] Topical delivery of seriniquinone for treatment of skin cancer and fungal infections is enabled by a liquid crystalline lamellar phase

RA Miguel, AS Hirata, GC Salata, AC Apolinário… - European Journal of …, 2024 - Elsevier
Seriniquinone (SQ) was initially described by our group as an antimelanoma drug candidate
and now also as an antifungal drug candidate. Despite its promising in vitro effects, SQ …

Optimization of nanoemulsified systems containing lamellar phases for co-delivery of celecoxib and endoxifen to the skin aiming for breast cancer chemoprevention …

G Mojeiko, AC Apolinário, GC Salata, M Chorilli… - Colloids and Surfaces A …, 2022 - Elsevier
We proposed an innovative nanoemulsified system containing lamellar phases (NLP)
produced by a low-energy method to enable the local-transdermal co-delivery of celecoxib …