Astrocyte morphology

KT Baldwin, KK Murai, BS Khakh - Trends in Cell Biology, 2023 - cell.com
Astrocytes are predominant glial cells that tile the central nervous system (CNS). A cardinal
feature of astrocytes is their complex and visually enchanting morphology, referred to as …

Immunological markers for central nervous system glia

H Huang, W He, T Tang, M Qiu - Neuroscience Bulletin, 2023 - Springer
Glial cells in the central nervous system (CNS) are composed of oligodendrocytes,
astrocytes and microglia. They contribute more than half of the total cells of the CNS, and are …

Molecular programs of regional specification and neural stem cell fate progression in macaque telencephalon

N Micali, S Ma, M Li, SK Kim, X Mato-Blanco… - Science, 2023 - science.org
During early telencephalic development, intricate processes of regional patterning and
neural stem cell (NSC) fate specification take place. However, our understanding of these …

Spatiotemporal molecular dynamics of the developing human thalamus

CN Kim, D Shin, A Wang, TJ Nowakowski - Science, 2023 - science.org
The thalamus plays a central coordinating role in the brain. Thalamic neurons are organized
into spatially distinct nuclei, but the molecular architecture of thalamic development is poorly …

Erratic and blood vessel-guided migration of astrocyte progenitors in the cerebral cortex

H Tabata, M Sasaki, M Agetsuma, H Sano… - Nature …, 2022 - nature.com
Astrocytes are one of the most abundant cell types in the mammalian brain. They play
essential roles in synapse formation, maturation, and elimination. However, how astrocytes …

Developmental origins of human cortical oligodendrocytes and astrocytes

L Yang, Z Li, G Liu, X Li, Z Yang - Neuroscience Bulletin, 2022 - Springer
Human cortical radial glial cells are primary neural stem cells that give rise to cortical
glutaminergic projection pyramidal neurons, glial cells (oligodendrocytes and astrocytes) …

An atlas of late prenatal human neurodevelopment resolved by single-nucleus transcriptomics

SI Ramos, ZM Mussa, EN Falk, B Pai, B Giotti… - Nature …, 2022 - nature.com
Late prenatal development of the human neocortex encompasses a critical period of
gliogenesis and cortical expansion. However, systematic single-cell analyses to resolve …

S100B is selectively expressed by gray matter protoplasmic astrocytes and myelinating oligodendrocytes in the developing CNS

J Du, M Yi, F Zhou, W He, A Yang, M Qiu, H Huang - Molecular Brain, 2021 - Springer
Studies on the development of central nervous system (CNS) primarily rely on the use of
specific molecular markers for different types of neural cells. S100B is widely being used as …

Human and mouse cortical astrocytes: a comparative view from development to morphological and functional characterization

E Degl'Innocenti, MT Dell'Anno - Frontiers in Neuroanatomy, 2023 - frontiersin.org
The vision of astroglia as a bare scaffold to neuronal circuitry has been largely overturned.
Astrocytes exert a neurotrophic function, but also take active part in supporting synaptic …

Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37

S Qin, Y Yuan, X Huang, Z Tan, X Hu, H Liu… - Nucleic acids …, 2022 - academic.oup.com
Topoisomerase IIA (TOP2a) has traditionally been known as an important nuclear enzyme
that resolves entanglements and relieves torsional stress of DNA double strands. However …