[HTML][HTML] Dopamine, serotonin and impulsivity

JW Dalley, JP Roiser - Neuroscience, 2012 - Elsevier
Impulsive people have a strong urge to act without thinking. It is sometimes regarded as a
positive trait but rash impulsiveness is also widely present in clinical disorders such as …

[HTML][HTML] Dopamine receptors and neurodegeneration

C Rangel-Barajas, I Coronel, B Florán - Aging and disease, 2015 - ncbi.nlm.nih.gov
Dopamine (DA) is one of the major neurotransmitters and participates in a number of
functions such as motor coordination, emotions, memory, reward mechanism …

Prefrontal dopamine and behavioral flexibility: shifting from an “inverted-U” toward a family of functions

SB Floresco - Frontiers in neuroscience, 2013 - frontiersin.org
Studies on prefrontal cortex (PFC) dopamine (DA) function have revealed its essential role
in mediating a variety of cognitive and executive functions. A general principle that has …

Value-free random exploration is linked to impulsivity

M Dubois, TU Hauser - Nature Communications, 2022 - nature.com
Deciding whether to forgo a good choice in favour of exploring a potentially more rewarding
alternative is one of the most challenging arbitrations both in human reasoning and in …

Dissociable contributions by prefrontal D1 and D2 receptors to risk-based decision making

JRS Onge, H Abhari, SB Floresco - Journal of Neuroscience, 2011 - Soc Neuroscience
Choices between certain and uncertain rewards of different magnitudes have been
proposed to be mediated by both the frontal lobes and the mesocorticolimbic dopamine (DA) …

Contributions of the orbitofrontal cortex to impulsive choice: interactions with basal levels of impulsivity, dopamine signalling, and reward-related cues

FD Zeeb, SB Floresco, CA Winstanley - Psychopharmacology, 2010 - Springer
Rationale Individual differences in impulsive decision-making may be critical determinants
of vulnerability to impulse control disorders and substance abuse, yet little is known of their …

Neural substrates underlying effort, time, and risk-based decision making in motivated behavior

MR Bailey, EH Simpson, PD Balsam - Neurobiology of Learning and …, 2016 - Elsevier
All mobile organisms rely on adaptive motivated behavior to overcome the challenges of
living in an environment in which essential resources may be limited. A variety of influences …

The effects of early life stress on impulsivity

EO Sanchez, DA Bangasser - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Elevated impulsivity is a symptom shared by various psychiatric disorders such as
substance use disorder, bipolar disorder, and attention-deficit/hyperactivity disorder …

Executive dysfunction in Parkinson's disease and timing deficits

KL Parker, D Lamichhane, MS Caetano… - Frontiers in integrative …, 2013 - frontiersin.org
Patients with Parkinson's disease (PD) have deficits in perceptual timing, or the perception
and estimation of time. PD patients can also have cognitive symptoms, including deficits in …

Animal models for bipolar disorder: from bedside to the cage

DKE Beyer, N Freund - International journal of bipolar disorders, 2017 - Springer
Bipolar disorder is characterized by recurrent manic and depressive episodes. Patients
suffering from this disorder experience dramatic mood swings with a wide variety of typical …