UK good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT)
were published in 2012 and 2015 for adult and paediatric patients, respectively. Here we …

Diabetes-related foot ulcers (DFUs) have a global prevalence of 6.3%, reaching 13% in
North America [1]. DFUs have a dismal prognosis, with 5-and 10-year survival rates of …

Non-tuberculous mycobacteria (NTM) is a collective name given to a group of more than 190
species of Mycobacterium. The clinical presentation for most NTM infections is non-specific …

Antibiotic overuse contributes to antibiotic resistance, which is a threat to public health.
Antibiotic stewardship is a practice dedicated to prescribing antibiotics only when necessary …

Introduction Dalbavancin is approved for acute bacterial skin and skin structure infections
(ABSSSIs) but offers a potential treatment option for complicated invasive gram-positive …

The use of continuous infusion to improve the therapeutic efficacy of time-dependent
antibiotics has been demonstrated. There is still a lack of data to safely perform these …

Variants in the microglial receptor TREM2 confer risk for multiple neurodegenerative
diseases. However, it remains unknown how this receptor functions on microglia to …

Background Reporting of outpatient parenteral antimicrobial therapy (OPAT) outcomes with
national benchmarking is key to informing service development and supporting quality …

Urinary tract infections (UTI) are one of the most common indications for antibiotic
prescriptions in the outpatient setting. Given rising rates of antibiotic resistance among …

In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-
related infections, an innovative care model combining outpatient parenteral antimicrobial …