Combined chemotherapy is a treatment method based on the simultaneous use of two or
more therapeutic agents; it is frequently necessary to produce a more effective treatment for …

Abstract Melatonin (N-acetyl-5-methoxy-tryptamine), which is generally considered as
pleiotropic and multitasking molecule, secretes from pineal gland at night under normal light …

Currently, neuropathic pain is an underestimated socioeconomic health problem affecting
millions of people worldwide, which incidence may increase in the next years due to …

The inhibitory effect of melatonin on cancer cell dissemination is well established, yet the
functional involvement of lncRNAs in melatonin signaling remains poorly understood. In this …

Radio-and chemotherapy are the most common cancer treatment modalities. They cause
acute and late side effects on normal tissues, which is a burden for delivery of a high dose of …

Cancers are serious life-threatening diseases which annually are responsible for millions of
deaths across the world. Despite many developments in therapeutic approaches for affected …

The evolutionarily ancient methoxyindoleamine, melatonin, has long perplexed investigators
by its versatility of functions and mechanisms of action, which include the regulation of …

The pineal gland-derived indoleamine hormone, melatonin, regulates multiple cellular
processes, ranging from chronobiology, proliferation, apoptosis, and oxidative damage to …

Obesity is a chronic condition whose management is a critical challenge for physicians. The
scientific community has increased its focus on the molecular mechanisms involved in …

Cervical cancer is one of the most common cancers between women and is known as the
third leading cause of female cancer related deaths annually. Its detection in early stages …