The natriuretic peptide family consists of three biologically active peptides: atrial natriuretic
peptide (ANP), brain (or B-type) natriuretic peptide (BNP), and C-type natriuretic peptide …

The biology of the natriuretic peptide (NP) system is complex, yet highly phylogenetically
preserved. It regulates salt and water handling, promotes vasodilatation, and exerts …

The mammalian natriuretic peptide family consists of atrial (ANP), brain [B-type; BNP] and C-
type natriuretic peptide (CNP) and three receptors, natriuretic receptors-A (NPR-A),-B (NPR …

In cardiac myocytes, the stimulation of p38 MAPK by the MAPKK, MKK6, activates the
transcription factor, NF-κB, and protects cells from apoptosis. In the present study in primary …

Three hallmark features of the cardiac hypertrophic growth program are increases in cell
size, sarcomeric organization, and the induction of certain cardiac-specific genes. All three …

The liganded vitamin D receptor (VDR) is thought to play an important role in controlling
cardiac function. Specifically, this system has been implicated as playing an antihypertrophic …

The natriuretic peptides, atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and
C-type natriuretic peptide (CNP), are a family of polypeptide mediators exerting numerous …

Application of mechanical strain to neonatal rat ventricular myocytes in culture evokes
changes in gene expression reminiscent of those that occur with hypertrophy in vivo, such …

The natriuretic peptides (NPs) are a group of peptide hormones that play important roles in
the control of renal, cardiovascular, endocrine, and skeletal homeostasis. Atrial NP (ANP) …

Natriuretic peptides and nitric oxide play important roles in cardiovascular and renal
physiology and disease. The natriuretic peptides—atrial natriuretic peptide, brain natriuretic …