The wide application of nanomaterials in consumer and medical products has raised
concerns about their potential adverse effects on human health. Thus, more and more …

Nanotoxicology studies toxicity of nanomaterials and has been widely applied in biomedical
researches to explore toxicity of various biological systems. Investigating biological systems …

Neoantigens play important roles in cancer immunotherapy. Current methods used for
neoantigen prediction focus on the binding between human leukocyte antigens (HLAs) and …

Tumor-specific neoantigens have attracted much attention since they can be used as
biomarkers to predict therapeutic effects of immune checkpoint blockade therapy and as …

The sweetpotato whitefly Bemisia tabaci is a highly destructive agricultural and ornamental
crop pest. It damages host plants through both phloem feeding and vectoring plant …

Motivation Many biological processes are governed by protein–ligand interactions. One
such example is the recognition of self and non-self cells by the immune system. This …

Predicting peptide binding affinity with human leukocyte antigen (HLA) is a crucial step in
developing powerful antitumor vaccine for cancer immunotherapy. Currently available …

Interactions between human leukocyte antigens (HLAs) and peptides play a critical role in
the human immune system. Accurate computational prediction of HLA-binding peptides can …

Drug discovery is time-consuming, expensive, and predominantly follows the “one drug→
one target→ one disease” paradigm. With the rapid development of systems biology and …

During the COVID-19 pandemic we utilized an AI-driven T cell epitope prediction tool, the
NEC Immune Profiler (NIP) to scrutinize and predict regions of T cell immunogenicity …