Mast cells and their mediators have been implicated in the pathogenesis of asthma and
allergy for decades. Allergic asthma is a complex chronic lung disease in which several …

Natural killer (NK) cells play critical roles in host defense against infectious agents or
neoplastic cells. NK cells provide a rapid innate immune response including the killing of …

Background The first 24 h of infection represent a critical time window in interactions
between pathogens and host tissue. However, it is not possible to study such early events in …

Background Studies using mouse models have revealed that mast cell progenitors are
recruited from the blood circulation to the lung during acute allergic airway inflammation …

Exploring the origin and regulatory role of mast cells in as... : Current Opinion in Allergy and
Clinical Immunology Exploring the origin and regulatory role of mast cells in asthma : Current …

Influenza A virus (IAV) is a respiratory pathogen that infects millions of people each year.
Both seasonal and pandemic strains of IAV are capable of causing severe respiratory …

IL-33 and its receptor ST2, as well as mast cells and their mediators, have been implicated
in the development of chronic obstructive pulmonary disease (COPD). However, whether …

Abstract Interleukin (IL)‐33 released from airway epithelial cells plays a vital role in shaping
type 2 immune responses by binding to the ST2 receptor present in many immune cells …

Mast cells (MCs) are found mainly at the anatomical sites exposed to the external
environment; thus, they are localized close to blood vessels, lymphatic vessels, and a …

Mast cells, widely residing in connective tissues and on mucosal surfaces, play significant
roles in battling against influenza A viruses. To gain further insights into the host cellular …