Free radical-mediated damage of the gall bladder epithelium predisposes to the
development of both gall bladder inflammation and gallstone formation, which often coexist …

Osteoporotic fractures are a public health problem and their incidence and subsequent
economic and social costs are expected to rise in the next future. Different drugs have been …

Melatonin (N-asetil-5-metoksitriptamin, Şekil 1) sentezinde birinci basamak triptofanın
pinealositler içine alınması ve orada pineal bir enzim olan N-asetiltransferaz (NAT) …

Background We aimed to identify the adverse effects of nonsteroidal anti-inflammatory drugs
(NSAIDs) and antithrombotics on the upper gastrointestinal (GI) mucosa in a clinical setting …

The anti‐catabolic bisphosphonate alendronate is considered as the first‐line medical
treatment in post‐menopausal osteoporosis; but several side effects, including gastric …

Melatonin uzun zamandan beri bilinen pineal bez hormunudur. Temel olarak immün
modülatuvar, gün içi ve mevsimsel ritmi ayarlayıcı, uyku düzenleyici etkileri vardır. Tüm …

Melatonin is a powerful hormone and antioxidant with numerous effects on the metabolism
and the health of humans. Available as a dietary supplement in the United States since …

Bisphosphonates are widely used for the treatment of bone diseases, including
hypercalcemia and osteoporosis. However, the bioavailability (BA) of orally administered …

Background It has been reported that simvastatin, a statin commonly prescribed for its anti-
inflammatory and antioxidant effects, has gastroprotective effects in indomethacin and …

Bisphosphonates (BPs) have became the treatment of choice for the prevention of skeletal
complications in cancer patients with bone metastases as well as in patients suffering from …