The dimensionality of cytometry data has strongly increased in the last decade, and in many
situations the traditional manual downstream analysis becomes insufficient. The field is …

Recently emerged mass cytometry (cytometry by time‐of‐flight [CyTOF]) technology permits
the identification and quantification of inherently diverse cellular systems, and the …

Natural killer (NK) cells are cytotoxic effector cells that target and lyse virally infected cells;
many viruses therefore encode mechanisms to escape such NK cell killing. Here, we …

Introduction Clinical disadvantages of initiating ART at low CD4 counts have been clearly
demonstrated but whether any excess risk remains even after reaching relatively high/safe …

Highly exposed seronegative (HESN) individuals present a unique setting to study
mechanisms of protection against HIV acquisition. As natural killer (NK) cell activation and …

Despite progress in preexposure prophylaxis, the number of newly diagnosed cases with
HIV-1 remains high, highlighting the urgent need for preventive and therapeutic strategies to …

Natural killer (NK) cells are critical modulators of HIV transmission and disease. Recent
evidence suggests a loss of NK cell cytotoxicity during aging, yet analysis of NK cell biology …

Despite efficient virological suppression on antiretroviral therapy (ART), people living with
HIV (PLWH), experience an increased burden of premature co-morbidities, such as cancer …

Abstract Purpose of Review This review describes how advances in CyTOF and high-
dimensional analysis methods have furthered our understanding of HIV transmission …

Natural killer (NK) cells are critical modulators of HIV transmission and disease. While recent
evidence suggests a loss of NK cell cytotoxicity during aging, a compound analysis of NK …