The neuroinflammatory response that is elicited after spinal cord injury contributes to both
tissue damage and reparative processes. The complex and dynamic cellular and molecular …

An important component for successful translation of cell replacement‐based therapies into
clinical practice is the utilization of large animal models to conduct efficacy and/or safety cell …

Currently, systemic immunosuppression is used in vascularized composite
allotransplantation (VCA). This treatment has considerable side effects and reduces the …

Hepatitis E virus (HEV) causes self-limited acute hepatitis in immunocompetent individuals
and can establish chronic infection in solid organ transplant recipients taking …

Optogenetic technologies have been the subject of great excitement within the scientific
community for their ability to demystify complex neurophysiological pathways in the central …

Objective Nerve allografts offer many advantages in the reconstruction of peripheral nerve
gaps: they retain their native microstructure, contain pro-regenerative Schwann cells, are …

Neural stem cell (NSC) transplantation has been reported to be a leading strategy to
stimulate neuroplasticity, repair neuronal loss and promote the morphologic and functional …

Background A well-characterized method has not yet been established to reproducibly,
efficiently, and safely isolate large numbers of clinical-grade multipotent human neural stem …

Background: In vascularized composite allotransplantation, medication nonadherence leads
to increased acute rejections. Improving medication adherence would improve overall …

Improved functional recovery after spinal cord injury by transplantation of induced
pluripotent stem cell-derived neural stem/progenitor cells (iPSC-NPCs) has been reported …