Genetic and biological hallmarks of colorectal cancer

J Li, X Ma, D Chakravarti, S Shalapour… - Genes & …, 2021 - genesdev.cshlp.org
Colorectal cancer has served as a genetic and biological paradigm for the evolution of solid
tumors, and these insights have illuminated early detection, risk stratification, prevention …

Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer

H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

Circulating tumour cells for early detection of clinically relevant cancer

R Lawrence, M Watters, CR Davies, K Pantel… - Nature Reviews Clinical …, 2023 - nature.com
Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early
detection are paramount to reducing cancer-related deaths and improving patient outcomes …

Signaling pathways involved in colorectal cancer: Pathogenesis and targeted therapy

Q Li, S Geng, H Luo, W Wang, YQ Mo, Q Luo… - … and Targeted Therapy, 2024 - nature.com
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality
worldwide. Its complexity is influenced by various signal transduction networks that govern …

Liquid biopsy in cancer current: status, challenges and future prospects

L Ma, H Guo, Y Zhao, Z Liu, C Wang, J Bu… - … and Targeted Therapy, 2024 - nature.com
Cancer has a high mortality rate across the globe, and tissue biopsy remains the gold
standard for tumor diagnosis due to its high level of laboratory standardization, good …

Advances in tests for colorectal cancer screening and diagnosis

SCH Chan, JQ Liang - Expert review of molecular diagnostics, 2022 - Taylor & Francis
Introduction Colorectal cancer (CRC) is the second leading cause of cancer-related deaths
globally. Nonetheless, with early detection of CRC or its precancerous lesions, mortality, and …

Colorectal cancer: Genetic alterations, novel biomarkers, current therapeutic strategies and clinical trials

M Housini, B Dariya, N Ahmed, A Stevens, H Fiadjoe… - Gene, 2024 - Elsevier
Colorectal cancer (CRC) is the third most commonly detected cancer with a serious global
health issue. The rates for incidence and mortality for CRC are alarming, especially since …

Clinical application of liquid biopsy in colorectal cancer: detection, prediction, and treatment monitoring

XY Tao, QQ Li, Y Zeng - Molecular Cancer, 2024 - Springer
Colorectal cancer (CRC) is one of the most prevalent malignancies affecting the
gastrointestinal tract and is ranked third among cancers with the highest incidence and …

[HTML][HTML] Liquid biopsy in the clinical management of cancers

HY Ho, KS Chung, CM Kan, SC Wong - International Journal of Molecular …, 2024 - mdpi.com
Liquid biopsy, a noninvasive diagnosis that examines circulating tumor components in body
fluids, is increasingly used in cancer management. An overview of relevant literature …

Circulating tumor cells from enumeration to analysis: Current challenges and future opportunities

YP Yang, TM Giret, RJ Cote - Cancers, 2021 - mdpi.com
Simple Summary With estimated numbers of 1–10 per mL of blood, circulating tumor cells
(CTCs) are extremely rare compared to white (a few million) or red (billions) blood cells …