How statistically fragile are randomized controlled trials comparing quadriceps tendon autografts with hamstring or bone‐patellar tendon‐bone autografts in anterior …
J Dworsky‐Fried, L Bernardini… - Knee Surgery …, 2024 - Wiley Online Library
Purpose To determine the statistical fragility of randomized controlled trials (RCTs) which
compare the use of quadriceps tendon (QT) autografts to either hamstring tendon (HT) or …
compare the use of quadriceps tendon (QT) autografts to either hamstring tendon (HT) or …
Forced randomization: the what, why, and how
K Carter, O Kuznetsova, V Anisimov, J Krisam… - BMC medical research …, 2024 - Springer
Background When running a randomized controlled trial (RCT), a clinical site may face a
situation when an eligible trial participant is to be randomized to the treatment that is not …
situation when an eligible trial participant is to be randomized to the treatment that is not …
Incertus. jl--The Julia Lego Blocks for Randomized Clinical Trial Designs
Y Ryeznik, O Sverdlov - arXiv preprint arXiv:2407.14248, 2024 - arxiv.org
In this paper, we present Insertus. jl, the Julia package that can help the user generate a
randomization sequence of a given length for a multi-arm trial with a pre-specified target …
randomization sequence of a given length for a multi-arm trial with a pre-specified target …
Understanding an impact of patient enrollment pattern on predictability of central (unstratified) randomization in a multi‐center clinical trial
J Krisam, Y Ryeznik, K Carter… - Statistics in …, 2024 - Wiley Online Library
In a multi‐center randomized controlled trial (RCT) with competitive recruitment, eligible
patients are enrolled sequentially by different study centers and are randomized to treatment …
patients are enrolled sequentially by different study centers and are randomized to treatment …
Maximum Tolerated Imbalance Randomization: Theory and Practice
O Sverdlov, K Carter, C Cassarly, Y Ryeznik… - … : Clinical Trial Design …, 2024 - Springer
Maximum tolerated imbalance (MTI) randomization is a class of restricted randomization
procedures that control treatment imbalance within pre-specified limits while lowering …
procedures that control treatment imbalance within pre-specified limits while lowering …
Randomization: Theory and Practice
O Sverdlov, K Carter, C Cassarly, Y Ryeznik… - … : Clinical Trial Design … - books.google.com
Randomization in clinical trials refers to the allocation of trial participants to treatment groups
through a process governed by chance (Wittes, 2005). The merits of randomization in …
through a process governed by chance (Wittes, 2005). The merits of randomization in …