A review of CT-based fracture risk assessment with finite element modeling and machine learning

I Fleps, EF Morgan - Current osteoporosis reports, 2022 - Springer
Abstract Purpose of Review We reviewed advances over the past 3 years in assessment of
fracture risk based on CT scans, considering methods that use finite element models …

Hierarchical biomechanics: concepts, bone as prominent example, and perspectives beyond

C Hellmich, N Ukaj, B Smeets… - Applied …, 2022 - asmedigitalcollection.asme.org
The main motivation for “hierarchical biomechanics” is that the wide variability of mechanical
properties encountered at the macroscopic scale may be traced back to just a few …

[HTML][HTML] Coupling systems biology with multiscale mechanics, for computer simulations of bone remodeling

S Scheiner, P Pivonka, C Hellmich - Computer Methods in Applied …, 2013 - Elsevier
Bone remodeling is a process involving removal of mature bone tissue and subsequent
formation of new bone tissue. This process is driven by complex actions of biological cells …

Poromicromechanics reveals that physiological bone strains induce osteocyte-stimulating lacunar pressure

S Scheiner, P Pivonka, C Hellmich - Biomechanics and modeling in …, 2016 - Springer
Mechanical loads which are macroscopically acting onto bony organs, are known to
influence the activities of biological cells located in the pore spaces of bone, in particular so …

Predicting the yield of the proximal femur using high-order finite-element analysis with inhomogeneous orthotropic material properties

Z Yosibash, D Tal, N Trabelsi - … Transactions of the …, 2010 - royalsocietypublishing.org
High-order finite-element (FE) analyses with inhomogeneous isotropic material properties
have been shown to predict the strains and displacements on the surface of the proximal …

[HTML][HTML] Intravoxel bone micromechanics for microCT-based finite element simulations

R Blanchard, A Dejaco, E Bongaers, C Hellmich - Journal of biomechanics, 2013 - Elsevier
While micro-FE simulations have become a standard tool in computational biomechanics,
the choice of appropriate material properties is still a relevant topic, typically involving …

Predicting the stiffness and strength of human femurs with real metastatic tumors

Z Yosibash, RP Mayo, G Dahan, N Trabelsi, G Amir… - Bone, 2014 - Elsevier
Background Predicting patient specific risk of fracture in femurs with metastatic tumors and
the need for surgical intervention are of major clinical importance. Recent patient-specific …

Prosthetic femoral stem for use in high impact hip replacement

JC Chow, BN Rindal, N Slater, JA Butters - US Patent 8,992,531, 2015 - Google Patents
A6B 7/5(2006.01)(57) ABSTRACT A6 IB 7/16(2006.01) A total hip femoral prosthesis
provides a shortened neck and A6 IF 2/36(2006.01) more proximal coating level …

Patient-specific finite-element analyses of the proximal femur with orthotropic material properties validated by experiments

N Trabelsi, Z Yosibash - 2011 - asmedigitalcollection.asme.org
Patient-specific high order finite-element (FE) models of human femurs based on
quantitative computer tomography (QCT) with inhomogeneous orthotropic and isotropic …

A comparative study of orthotropic and isotropic bone adaptation in the femur

DM Geraldes, ATM Phillips - International journal for numerical …, 2014 - Wiley Online Library
Functional adaptation of the femur has been studied extensively by embedding remodelling
algorithms in finite element models, with bone commonly assumed to have isotropic material …