The term “click chemistry” describes a class of organic transformations that were developed
to make chemical synthesis simpler and easier, in essence allowing chemists to combine …

After the protocol-related indecisive clinical trial of Oxygent, a perfluorooctylbromide/
phospholipid nanoemulsion, in cardiac surgery, that often unduly assigned the observed …

Nuclear medicine is defined as the use of radionuclides for diagnostic and therapeutic
applications. The imaging modalities positron emission tomography (PET) and single …

Bioorthogonal chemistry represents plenty of highly efficient and biocompatible reactions
that proceed selectively and rapidly in biological situations without unexpected side …

In recent years, several catalyst-free site-specific reactions have been investigated for the
efficient conjugation of biomolecules, nanomaterials, and living cells. Representative …

Microbubble‐enabled focused ultrasound (MB‐FUS) has revolutionized nano and molecular
drug delivery capabilities. Yet, the absence of longitudinal, systematic, quantitative studies of …

Advances in diagnostic and imaging capabilities have allowed cancers to be detected
earlier and characterized more robustly. These strategies have recently branched into …

Substituted derivatives of the DOTA framework are of general interest to alter chelate
properties and facilitate the conjugation of chelates to other molecular structures. However …

The PtIV prodrug iproplatin has been actively loaded into liposomes using a calcium acetate
gradient, achieving a 3‐fold enhancement in drug concentration compared to passive …

The blood-brain-barrier stops many imaging agents and therapeutics from being delivered
to the brain that could fight central nervous system diseases such as Alzheimer's Disease …