Oncolytic viruses: newest frontier for cancer immunotherapy

MM Rahman, G McFadden - Cancers, 2021 - mdpi.com
Simple Summary Oncolytic viruses (OVs) are viruses that selectively target and kill cancer
cells while sparing normal ones. OVs are from diverse families of viruses, but naturally …

Oncolytic virotherapy in cancer treatment: challenges and optimization prospects

L Chen, M Zuo, Q Zhou, Y Wang - Frontiers in Immunology, 2023 - frontiersin.org
Oncolytic viruses (OVs) are emerging cancer therapeutics that offer a multifaceted
therapeutic platform for the benefits of replicating and lysing tumor cells, being engineered …

Combination of SABR with anti-PD-1 in oligoprogressive non-small cell lung cancer and melanoma: results of a prospective multicenter observational study

R Chicas-Sett, J Zafra, D Rodriguez-Abreu… - International Journal of …, 2022 - Elsevier
Purpose The percentage of patients with metastatic non-small cell lung cancer (NSCLC) and
melanoma who benefit from anti–programmed cell death protein 1 (anti-PD-1) is low owing …

High-throughput monoclonal antibody discovery from phage libraries: challenging the current preclinical pipeline to keep the pace with the increasing mAb demand

N Zambrano, G Froechlich, D Lazarevic, M Passariello… - Cancers, 2022 - mdpi.com
Simple Summary Monoclonal antibodies are increasingly used for a broad range of
diseases. Rising demand must face with time time-consuming and laborious processes to …

[HTML][HTML] International consensus on radiotherapy in metastatic non-small cell lung cancer

Z Zhu, J Ni, X Cai, S Su, H Zhuang, Z Yang… - Translational Lung …, 2022 - ncbi.nlm.nih.gov
Background Lung cancer is the leading cause of cancer-related death worldwide, with non-
small cell lung cancer (NSCLC) accounting for most cases. While radiotherapy has …

Immunostimulatory effects of radiotherapy for local and systemic control of melanoma: A review

J Takahashi, S Nagasawa - International journal of molecular sciences, 2020 - mdpi.com
Recently, modern therapies involving immune checkpoint inhibitors, cytokines, and oncolytic
virus have been developed. Because of the limited treatment effect of modern therapy alone …

[HTML][HTML] GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer

NR De Dios, A Navarro-Martin, C Cigarral… - World journal of …, 2022 - ncbi.nlm.nih.gov
Non-small cell lung cancer (NSCLC) is a heterogeneous disease accounting for
approximately 85% of all lung cancers. Only 17% of patients are diagnosed at an early …

Improving the efficacy of combined radiotherapy and immunotherapy: focusing on the effects of radiosensitivity

Z Gao, Q Zhao, Y Xu, L Wang - Radiation Oncology, 2023 - Springer
Cancer treatment is gradually entering an era of precision, with multitude studies in gene
testing and immunotherapy. Tumor cells can be recognized and eliminated by the immune …

Gene signature based on B cell predicts clinical outcome of radiotherapy and immunotherapy for patients with lung adenocarcinoma

L Han, H Shi, Y Luo, W Sun, S Li, N Zhang… - Cancer …, 2020 - Wiley Online Library
Lung adenocarcinoma (LUAD) is the most common and lethal cancer worldwide.
Radiotherapy (RT) is widely used at all stages of LUAD, and the development of …

Immunoradiotherapy for NSCLC: mechanisms, clinical outcomes, and future directions

H Weishan, Z Donglin, D Guangmei, L Wenya… - Clinical and …, 2024 - Springer
Non-small-cell lung cancer (NSCLC) has an extremely low 5-year survival rate, with the only
effective treatment being immunoradiotherapy (iRT). Here, we review the progress of clinical …