A primer on congenital anomalies of the kidneys and urinary tracts (CAKUT)
V Murugapoopathy, IR Gupta - … Journal of the American society of …, 2020 - journals.lww.com
Congenital anomalies of the kidneys and urinary tracts (CAKUT) are disorders caused by
defects in the development of the kidneys and their outflow tracts. The formation of the …
defects in the development of the kidneys and their outflow tracts. The formation of the …
Nephron overload as a therapeutic target to maximize kidney lifespan
Kidney lifespan is a patient-oriented outcome that provides much needed context for
understanding chronic kidney disease (CKD). Nephron endowment, age-associated decline …
understanding chronic kidney disease (CKD). Nephron endowment, age-associated decline …
Visualization of renal glomeruli in human native kidneys with sensing ultrasound localization microscopy
Objectives Kidney diseases significantly impact individuals' quality of life and strongly
reduce life expectancy. Glomeruli play a crucial role in kidney function. Current imaging …
reduce life expectancy. Glomeruli play a crucial role in kidney function. Current imaging …
SGLT2 inhibition requires reconsideration of fundamental paradigms in chronic kidney disease,'diabetic nephropathy', IgA nephropathy and podocytopathies with …
HJ Anders, AJ Peired… - Nephrology Dialysis …, 2022 - academic.oup.com
Abstract In 2020, the Dapagliflozin and Prevention of Adverse Outcomes in Chronic Kidney
Disease (DAPA-CKD) trial first demonstrated that inhibition of the sodium–glucose …
Disease (DAPA-CKD) trial first demonstrated that inhibition of the sodium–glucose …
Chronic kidney disease induced by cadmium and diabetes: A quantitative case-control study
Kidney disease associated with chronic cadmium (Cd) exposure is primarily due to proximal
tubule cell damage. This results in a sustained decline in glomerular filtration rate (GFR) and …
tubule cell damage. This results in a sustained decline in glomerular filtration rate (GFR) and …
An improved method for estimating nephron number and the association of resulting nephron number estimates with chronic kidney disease outcomes
Background Nephron number can be estimated from glomerular density and cortical
volume. However, because of measurement biases, this approach needs refinement …
volume. However, because of measurement biases, this approach needs refinement …
The NOAEL equivalent of environmental cadmium exposure associated with GFR reduction and chronic kidney disease
Cadmium (Cd) is a highly toxic metal pollutant present in virtually all food types. Health
guidance values were established to safeguard against excessive dietary Cd exposure. The …
guidance values were established to safeguard against excessive dietary Cd exposure. The …
Quantitative renal magnetic resonance imaging: magnetic resonance urography
JD Grattan-Smith, J Chow, S Kurugol, RA Jones - Pediatric radiology, 2022 - Springer
The goal of functional renal imaging is to identify and quantitate irreversible renal damage
and nephron loss, as well as potentially reversible hemodynamic changes. MR urography …
and nephron loss, as well as potentially reversible hemodynamic changes. MR urography …
Renal MRI: from nephron to NMR signal
Renal diseases pose a significant socio‐economic burden on healthcare systems. The
development of better diagnostics and prognostics is well‐recognized as a key strategy to …
development of better diagnostics and prognostics is well‐recognized as a key strategy to …
Evidence Linking Cadmium Exposure and β2-Microglobulin to Increased Risk of Hypertension in Diabetes Type 2
The most common causes of chronic kidney disease, diabetes, and hypertension are
significant public health issues worldwide. Exposure to the heavy metal pollutant, cadmium …
significant public health issues worldwide. Exposure to the heavy metal pollutant, cadmium …