The brain is arguably the most complex organ. The branched and extended morphology of
nerve cells, their subcellular complexity, the multiplicity of brain cell types as well as their …

The opioid epidemic has led to a serious examination of the use of opioids for the treatment
of pain. Opioid drugs are effective due to the expression of opioid receptors throughout the …

Understanding how protein–protein interaction networks in the brain give rise to cognitive
functions necessitates their characterization in live animals. However, tools available for this …

Protein analysis under biological conditions is now regarded as indispensable for
understanding the structure and function of proteins, in addition to in vitro studies using …

Flourished in the past two decades, fluorescent probe technology provides researchers with
accurate and efficient tools for in situ imaging of biomarkers in living cells and tissues and …

Neurotransmitter receptors are essential components of synapses for communication
between neurons in the brain. Because the spatiotemporal expression profiles and …

Background Expression of the mu-opioid receptor (MOR) is associated with poor long-term
outcomes in various types of cancer. The association between MOR expression and clinical …

Pharmacological modulation of cannabinoid receptor type 2 (CB2R) holds promise for the
treatment of neuroinflammatory disorders, such as Alzheimer's disease. Despite the …

Small molecular tool compounds play an essential role in the study of G protein-coupled
receptors (GPCRs). However, tool compounds most often occupy the orthosteric binding …

Chronic pain affects 20% to 45% of the global population and is often associated with the
development of anxio‐depressive disorders. Treatment of this debilitating condition remains …