Bacterial extracellular vesicles and their interplay with the immune system

E Doré, E Boilard - Pharmacology & Therapeutics, 2023 - Elsevier
The mammalian intestinal tract harbors trillions of microorganisms confined within this space
by mucosal barriers. Despite these barriers, bacterial components may still be found …

Advances in Electrochemical Biosensors for the Detection of Common Oral Diseases

C Liu, C Guan, Y Li, Z Li, Y Wang… - Critical Reviews in …, 2024 - Taylor & Francis
Limiting and preventing oral diseases remains a major challenge to the health of
populations around the world, so finding ways to detect early-stage diseases (eg, caries …

Exploration of shared gene signatures and molecular mechanisms between periodontitis and nonalcoholic fatty liver disease

W Xu, Z Zhang, L Yao, B Xue, H Xi, X Wang… - Frontiers in genetics, 2022 - frontiersin.org
Background: Periodontitis is associated with periodontal tissue damage and teeth loss.
Nonalcoholic fatty liver disease (NAFLD) has an intimate relationship with periodontitis …

Factores de virulencia de los componentes de Porphyromona gingivalis: Una revisión narrativa

MJ Godínez-López, JP Loyola-Rodríguez… - Gaceta Médica de …, 2023 - saber.ucv.ve
La cavidad bucal es un ecosistema donde existen más de 700 especies de bacterias, en el
que las superficie de los dientes, tejidos blandos e incluso prótesis ofrecen nichos …

Porphyromonas gingivalis gingipains destroy the vascular barrier and reduce CD99 and CD99L2 expression to regulate transendothelial migration

Z Zou, J Fang, W Ma, J Guo, Z Shan, D Ma… - Microbiology …, 2023 - Am Soc Microbiol
Porphyromonas gingivalis is an important periodontal pathogen that can cause vascular
injury and invade local tissues through the blood circulation, and its ability to evade …

[HTML][HTML] Oral Pathobiont-Derived Outer Membrane Vesicles in the Oral–Gut Axis

EA Catalan, E Seguel-Fuentes, B Fuentes… - International Journal of …, 2024 - mdpi.com
Oral pathobionts are essential in instigating local inflammation within the oral cavity and
contribute to the pathogenesis of diseases in the gastrointestinal tract and other distant …

Investigating the role of a Tannerella forsythia HtrA protease in host protein degradation and inflammatory response

S Bloch, FF Hager-Mair, J Bacher, MB Tomek… - Frontiers in Oral …, 2024 - frontiersin.org
Introduction Degradation of host proteins by bacterial proteases leads to the subversion of
the host response and disruption of oral epithelial integrity, which is considered an essential …

Identification of bio-active secondary metabolites from Actinobacteria as potential drug targets against Porphyromonas gingivalis in oral squamous cell carcinoma …

Z Taj, I Chattopadhyay - In Silico Pharmacology, 2024 - Springer
Chronic periodontitis caused by the bacteria Porphyromonas gingivalis is thought to be a
risk factor for the advancement of oral squamous cell carcinoma (OSCC). Virulence factors …

A cleaved adhesin DNA vaccine targeting dendritic cell against Porphyromonas gingivalis–induced periodontal disease

X Fan, PY Qu, KF Luan, CY Sun… - Molecular Oral …, 2024 - Wiley Online Library
Abstract Background Arg‐gingipain A (RgpA) is the primary virulence factor of
Porphyromonas gingivalis and contains hemagglutinin adhesin (HA), which helps bacteria …

Porphyromonas gingivalis infection alters microRNA composition in extracellular vesicles

K Yoshida, K Yoshida, Y Mouri, A Takai… - Journal of Oral …, 2024 - Elsevier
Objectives Periodontitis, commonly associated with Porphyromonas gingivalis (Pg), involves
intricate alterations of oral intercellular interactions, in which extracellular vesicles (EVs) play …