Promises and pitfalls of using high‐throughput sequencing for diet analysis

A Alberdi, O Aizpurua, K Bohmann… - Molecular ecology …, 2019 - Wiley Online Library
The application of high‐throughput sequencing‐based approaches to DNA extracted from
environmental samples such as gut contents and faeces has become a popular tool for …

Metagenomics: tools and insights for analyzing next-generation sequencing data derived from biodiversity studies

A Oulas, C Pavloudi, P Polymenakou… - … and biology insights, 2015 - journals.sagepub.com
Advances in next-generation sequencing (NGS) have allowed significant breakthroughs in
microbial ecology studies. This has led to the rapid expansion of research in the field and …

Improving deep learning protein monomer and complex structure prediction using DeepMSA2 with huge metagenomics data

W Zheng, Q Wuyun, Y Li, C Zhang, PL Freddolino… - Nature …, 2024 - nature.com
Leveraging iterative alignment search through genomic and metagenome sequence
databases, we report the DeepMSA2 pipeline for uniform protein single-and multichain …

MEGAN community edition-interactive exploration and analysis of large-scale microbiome sequencing data

DH Huson, S Beier, I Flade, A Górska… - PLoS computational …, 2016 - journals.plos.org
There is increasing interest in employing shotgun sequencing, rather than amplicon
sequencing, to analyze microbiome samples. Typical projects may involve hundreds of …

The InterPro protein families database: the classification resource after 15 years

A Mitchell, HY Chang, L Daugherty… - Nucleic acids …, 2015 - academic.oup.com
Abstract The InterPro database (http://www. ebi. ac. uk/interpro/) is a freely available
resource that can be used to classify sequences into protein families and to predict the …

Rfam 12.0: updates to the RNA families database

EP Nawrocki, SW Burge, A Bateman… - Nucleic acids …, 2015 - academic.oup.com
The Rfam database (available at http://rfam. xfam. org) is a collection of non-coding RNA
families represented by manually curated sequence alignments, consensus secondary …

An evaluation of the accuracy and speed of metagenome analysis tools

S Lindgreen, KL Adair, PP Gardner - Scientific reports, 2016 - nature.com
Metagenome studies are becoming increasingly widespread, yielding important insights into
microbial communities covering diverse environments from terrestrial and aquatic …

The human mycobiome in health and disease

L Cui, A Morris, E Ghedin - Genome medicine, 2013 - Springer
The mycobiome, referring primarily to the fungal biota in an environment, is an important
component of the human microbiome. Despite its importance, it has remained understudied …

EBI Metagenomics in 2017: enriching the analysis of microbial communities, from sequence reads to assemblies

AL Mitchell, M Scheremetjew, H Denise… - Nucleic acids …, 2018 - academic.oup.com
Abstract EBI metagenomics (http://www. ebi. ac. uk/metagenomics) provides a free to use
platform for the analysis and archiving of sequence data derived from the microbial …

A review of bioinformatics tools for bio-prospecting from metagenomic sequence data

DD Roumpeka, RJ Wallace, F Escalettes… - Frontiers in …, 2017 - frontiersin.org
The microbiome can be defined as the community of microorganisms that live in a particular
environment. Metagenomics is the practice of sequencing DNA from the genomes of all …